Journal of Korean Traditional Oncology (대한암한의학회지)
- Volume 14 Issue 1
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- Pages.75-84
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- 2009
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- 1975-244X(pISSN)
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- 2765-4850(eISSN)
Study on the Anti-tumor Effect of Gekko
천룡(天龍)의 항암효과에 대한 고찰
- Ahn, Tae-Kyu (Liver-Immune Department of Oriental Medicine college, Daejeon University) ;
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Son, Chang-Gue
(Liver-Immune Department of Oriental Medicine college, Daejeon University) ;
- Jeong, Tae-Yong (Liver-Immune Department of Oriental Medicine college, Daejeon University) ;
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Yoo, Hwa-Seung
(Liver-Immune Department of Oriental Medicine college, Daejeon University) ;
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Cho, Jung-Hyo
(Liver-Immune Department of Oriental Medicine college, Daejeon University)
- 안태규 (대전대학교 한의과대학 간장 면역학 교실) ;
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손창규
(대전대학교 한의과대학 간장 면역학 교실) ;
- 정태영 (대전대학교 한의과대학 간장 면역학 교실) ;
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유화승
(대전대학교 한의과대학 간장 면역학 교실) ;
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조정효
(대전대학교 한의과대학 간장 면역학 교실)
- Published : 2009.12.28
Abstract
Gekko has been used for several diseases including cancer in Oriental medicine and fork herbalogy. Nevertheless, its origin as herbal medicine and its efficacy and mechanism as anti-tumor drug have not yet been thoroughly reported in Korea. This study aimed to investigate anti-tumor effect of Gekko through selected articles from cqvip database in China. In vitro and In vivo, Gekko could obviously inhibit tumor growth, induce tumor cells apoptosis, reduce micro-vessel density in tumor tissue through down regulating VEGF & bFGF protein expression, promote cytotoxicity of lymphocyte. Gekko could improve survival rate, relive clinical symptoms, improve quality of life, and relieve anti-tumor treatment reaction, suggesting that Gekko might be a effective anti-tumor drug.