Listeria Sepsis and Pneumonia in a Premature Neonate

산전 감염 후 발생한 폐혈증 및 폐렴을 동반한 미숙아 리스테리아증 1례

  • Park, Joon-Woo (Department of Pediatrics, College of Medicine, Hallym University) ;
  • Yoon, Jeong-Min (Department of Pediatrics, College of Medicine, Hallym University) ;
  • Sung, Tae-Jung (Department of Pediatrics, College of Medicine, Hallym University)
  • 박준우 (한림대학교 의과대학 소아과학교실) ;
  • 윤정민 (한림대학교 의과대학 소아과학교실) ;
  • 성태정 (한림대학교 의과대학 소아과학교실)
  • Published : 2009.05.31

Abstract

Listeria monocytogenes (L. monocytogenes) is a foodborne anaerobic gram-positive rod and the third most common pathogen for neonatal meningitis. Although the mortality and morbidity of L. monocytogenes infections are high, thus causing serious problems in Western populations, neonatal listeriosis is relatively rare in Eastern countries, including Korea. Possible routes for intrauterine infection or vertical transmission of L. monocytogenes include infected placentas and the reproductive tract. Intrauterine infections may cause chorioamnionitis, preterm labor, spontaneous abortion, stillbirth, or neonatal infection. A high index of suspicion and early empirical antibiotic treatment are critical to achieve a favorable prognosis for neonatal listeriosis. We managed a case of L. monocytogenes sepsis and pneumonia in a premature neonate born at 26 weeks of gestational age from an asymptomatic mother with culture-proven placental infection. The neonate was successively treated with ampicillin and gentamicin.

저자들은 태반에서 L. monocytogenes 균이 동정된 무증상 산모에서 출생한 $26^{+4}$주, 930g 초극소 저체중 출생아에서 리스테리아 조기 패혈증 및 폐렴이 발생하여 항생제 치료 후 호전된 1례를 경험하여 이를 문헌 고찰과 함께 보고하는 바이다.

Keywords

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