Surgical Outcome of Aneurysmal Subarachnoid Hemorrhage of Elderly Patients

고령의 뇌동맥류성 지주막하출혈 환자에서 수술적 치료 후 예후에 대한 임상적 고찰

  • Cheon, Se-Hun (Department of Neurosurgery, Korea University, School of Medicine) ;
  • Im, Dong-Jun (Department of Neurosurgery, Korea University, School of Medicine) ;
  • Ha, Seong-Gon (Department of Neurosurgery, Korea University, School of Medicine) ;
  • Gwon, Taek-Hyeon (Department of Neurosurgery, Korea University, School of Medicine) ;
  • Park, Jeong-Yul (Department of Neurosurgery, Korea University, School of Medicine) ;
  • Jeong, Yong-Gu (Department of Neurosurgery, Korea University, School of Medicine)
  • 천세훈 (고려대학교 의과대학 안산병원 신경외과학교실) ;
  • 임동준 (고려대학교 의과대학 안산병원 신경외과학교실) ;
  • 하성곤 (고려대학교 의과대학 안산병원 신경외과학교실) ;
  • 권택현 (고려대학교 의과대학 안산병원 신경외과학교실) ;
  • 박정율 (고려대학교 의과대학 안산병원 신경외과학교실) ;
  • 정용구 (고려대학교 의과대학 안산병원 신경외과학교실)
  • Published : 2009.03.30

Abstract

The number of elderly patients with cerebral aneurysm has markedly increased. We investigated the clinical characteristics and the surgical outcomes of cerebral aneurysms among elderly patients more than 65 years of age compared to a control group including patients less than 65. Materials and Methods : From March 2001 to May 2007, 590 patients with aneurysmal subarachnoid hemorrhage (SAH) were treated; among them, 88 patients (14.9%) more than 65 were candidates for this study. The variables included in the analysis were: age, gender, size and site of the aneurysm, the Hunt-Hess grade, size of the hematoma on the CT scan, and comorbidities. Results : The mean age was 69 (range 65-84 years), 72 patients (81%) were female, 72 of the patients had a Hunt-Hess grade of I-III, 37 patients (42%) had anterior communicating artery bleeds, and 13 patients (16.7%) had multiple aneurysms. The treatments consisted of neck clipping for 77 aneurysms and endovascular therapy for 11 aneurysms. Fifty eight patients (65.9%) had a favorable outcome and the overall mortality was 11.4%. The main causes of unfavorable outcomes among the elderly patients included a poor Hunt-Hess grade on admission and a concurrent intracerebral hematoma. Conclusions : The results of this study showed that advanced age was not a contra-indication to aneurysm surgery and early craniotomy can lead to a better outcome in elderly patients.

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