Journal of Life Science (생명과학회지)

Korean Society of Life Science (한국생명과학회)
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An Etiologic Study of Rabbit Dermatitis at Large Rabbit Farms in South Korea

집단 사육 되는 토끼에서 호발하는 피부병에 관한 병인론적 연구

  • Kim, Sung-Ho (College of Veterinary Medicine, Konkuk University) ;
  • Lee, Jae-Hoon (College of Veterinary Medicine, Konkuk University) ;
  • Chang, Hwa-Seok (College of Veterinary Medicine, Konkuk University) ;
  • Kang, Eun-Hee (Department of Clinical Pharmacology, School of Medicine, Kyung Hee University) ;
  • Chung, Dai-Jung (Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California-Davis) ;
  • Kim, Hwi-Yool (College of Veterinary Medicine, Konkuk University)
  • 김성호 (건국대학교 수의과대학 수의학과) ;
  • 이재훈 (건국대학교 수의과대학 수의학과) ;
  • 장화석 (건국대학교 수의과대학 수의학과) ;
  • 강은희 (경희대학교 의과대학 임상약리학) ;
  • 정다정 (캘리포니아 데이비스대학 수의과학대학 수의 외과&방사선학과) ;
  • 김휘율 (건국대학교 수의과대학 수의학과)
  • Published : 2009.11.30
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Abstract

This study was carried out between August and September 2007 to determine the causative agents and epidemiologic features of rabbit dermatitis in Korea. Rabbits were shipped to the laboratory in the College of Veterinary Medicine from 10 rabbit farms. A total of 520 hair, blood, and skin specimens collected from skin lesions of 40 rabbits with suspected dermatopathy were examined mycologically, bacteriologically, and parasitologically. The positive rates of dermatophytosis, bacterial skin dermatitis, and ectoparasite dermatitis were 95, 92.5, and 7.5%, respectively. The etiologic agents of dermatophytosis were identified as Trichophyton mentagrophyte (95%), non-dermatophytic filamentous fungi such as Aspergillus s(5%), and Cryptococcus humilocus (2.5%). With respect to bacteria-related skin dermatitis, Staphylococcus coagulase negative was the most common etiological agent. Staphylococcus aureus was the second most frequent causative agent. Most of the pathogenic isolates were resistant to tetracycline, and aminoglycosides such as amikacin and gentamicin were the most effective drugs against the pathologic bacteria isolated. Ectoparasites were rarely detected in this study. Only Psoroptes cuniculis was detected in 3 (7.5%) out of the 40 tested rabbits. The role of ectoparasites as a causative agent of dermatitis in rabbits in this study was minimal. Our results provide important information related to rabbit dermatitis treatments and researches.

본 실험은 2007년 8월에서 9월 동안, 집단 사육되는 토끼에서 피부병을 유발한 주 병원체를 확인하고 역학적인 특성을 조사하기 위해 실시되었다. 총 10개의 농장에서 임상적으로 피부병이 명확한 토끼들을 선별하여 실험에 공시하였다. 40마리의 토끼 피부병변에서 모발 및 피부 조직 520개를 채취하여 진균학적, 세균학적, 기생충학적으로 검사를 실시하였다. 피부사상균, 세균성 피부염 그리고 기생충성 피부염의 발병율은 각각 95%, 92.5% 그리고 7.5%로 나타났다. 진균 배양 결과에서 피부 사상균의 주된 원인체로 Trichophyton mentagrophyte (95%)가 가장 많이 검출되었고, 그 다음으로 Aspergillus s(5%)와 Cryptococcus humilocus (2.5%)가 순차적으로 검출되었다. 세균 배양 결과에서는 토끼의 세균성 피부염을 유발하는 원인체로 Staphylococcus coagulase가 가장 많이 검출되었고, Staphylococcus aureus가 두 번째로 많은 비율을 차지하였다. 이 연구에서는 외부 기생충의 검출은 낮게 나타났으며, Psoroptes cuniculi가 40마리의 토끼 중 3마리에서(7.5%) 검출되었다. 본 실험의 결과는 토끼 피부병 치료와 연구에 관련한 기초 정보를 제공할 것이라 판단된다.

Keywords

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