The Korean Journal of Food And Nutrition (한국식품영양학회지)

The Korean Society of Food and Nutrition (한국식품영양학회)
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Antioxidant and Antibacterial Activities of Ethyl Acetate Extract from Scutellaria baicalensis

황금(Scutellaria baicalensis)의 에틸 아세테이트 추출물의 항산화 및 항균 활성

  • Kim, Yong-Hyun (Dept. of Biology, College of Natural Science, Soonchunhyang University) ;
  • Paek, Jong-Yoon (Dept. of Biology, College of Natural Science, Soonchunhyang University) ;
  • Kwon, Hyun-Jung (Dept. of Biology, College of Natural Science, Soonchunhyang University) ;
  • Lee, Jae-Woo (Dept. of Food Nutrition, Gimcheon College) ;
  • Yoon, Ok-Hyun (Dept. of Food Nutrition, Gimcheon College) ;
  • Han, Man-Deuk (Dept. of Biology, College of Natural Science, Soonchunhyang University)
  • Published : 2009.09.30
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Abstract

This study aimed to determine the antioxidant and antibacterial effects of solvent extracts from Scutellaria baicalensis. The S. baicalensis was successively extracted with 5 kinds of solvents. The obtained samples were as follows; hexan fraction (IPK-1), chloroform fraction(IPK-2), ethyl acetate fraction(IPK-3), butanol fraction(IPK-4), and water fraction(IPK-5). These extracts were determined to process antibacterial effects using a paper disc method against 18 species of human pathogenic bacteria, antioxidant activity using 1,1-diphenyl-2-picrylhydrazyl(DPPH) method and inhibiting ability of linoleic acid autoxidation. Extracts of S. baicalensis has shown selective antibacterial effects on various strains of bacteria. Ethyl acetate fraction(IPK-3) showed the highest antimicrobial activity against selective bacteria, such as Staphylococcus aureus 285, S. aureus 503. In antioxidant activity test, free radical scavenger activity of IPK-3 fraction was 92% compared with BHA at the same concentration, while lipid peroxidation inhibition was 48%. These results suggest that IPK-3 fraction of S. baicalensis could be suitable in development of antimicrobial and antioxidant agents.

Keywords

References

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