Bulletin of the Korean Chemical Society

Korean Chemical Society (대한화학회)
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Synthesis of 3'(β)-C-methyl Carbodine Analogues as Potential Anti-HCV Agents

  • Li, Hua (BK21- Project Team, College of Pharmacy, Chosun University) ;
  • Baik, Young-Chan (Hawon Pharmaceuticals Co.,) ;
  • Hong, Joon-Hee (BK21- Project Team, College of Pharmacy, Chosun University)
  • Published : 2009.05.20
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Abstract

The synthetic route of novel 3′-C-methyl carbodine analogue is described. The construction of tertiary alcohol at 3′- position of carbodine analogues was successfully made via sequential [3,3]-sigmatropic rearrangement, ring-closing metathesis (RCM) and stereoselective dihydroxylation reactions starting from ethyl glycolate.

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References

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