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Pulmonary Adenocarcinoma with a Micropapillary Pattern Detected by Bronchial Washing - A Brief Case Report -

폐의 미세유두상 패턴을 보이는 선암종의 기관지세척 세포소견 - 짧은 증례보고 -

  • Park, Jae-Hong (Department of Pathology, Gachon University, Gil Hospital) ;
  • Ha, Seung-Yeon (Department of Pathology, Gachon University, Gil Hospital) ;
  • Cho, Hyun-Yee (Department of Pathology, Gachon University, Gil Hospital) ;
  • Chung, Dong-Hae (Department of Pathology, Gachon University, Gil Hospital) ;
  • Kim, Na-Rae (Department of Pathology, Gachon University, Gil Hospital) ;
  • Park, Sang-Hui (Department of Pathology, Gachon University, Gil Hospital)
  • 박재홍 (가천의과학대학교 길병원 병리과) ;
  • 하승연 (가천의과학대학교 길병원 병리과) ;
  • 조현이 (가천의과학대학교 길병원 병리과) ;
  • 정동해 (가천의과학대학교 길병원 병리과) ;
  • 김나래 (가천의과학대학교 길병원 병리과) ;
  • 박상희 (가천의과학대학교 길병원 병리과)
  • Published : 2008.09.30

Abstract

Adenocarcinomas with micropapillary patterns are generally aggressive and show lymphotropism. Only a few reports on pulmonary adenocarcinoma with micropapillary patterns have described cytologic findings. A 70-year-old Korean woman was admitted to the hospital because of intermittent dry cough and chest pain. Cytology after bronchial washing showed neoplastic cells in small, angulated, cohesive clusters consisting of 3-20 cells without a fibrovascular core. The resected right middle lobe showed a tumor occupying almost the entire lobe. Histologically, about 90% of neoplastic cells proliferated with micro papillary morphology in the background of bronchioloalveolar carcinoma. Cytologic smears of a bronchial washing showing tumor cells in small, cohesive clusters without a fibrovascular core may indicate an adenocarcinoma with micropapillary pattern.

Keywords

References

  1. Amin MB, Tamboli P, Merchant SH, et al. Micropapillary component in lung adenocarcinoma. A distinctive histologic feature with possible prognostic significance. Am J Surg Pathol 2002;26:358-64 https://doi.org/10.1097/00000478-200203000-00010
  2. Hoshi R, Tsuzuku M, Horai T, Ishikawa Y, Satoh Y. Micropapillary clusters in early-stage lung adenocarcinomas. A distinct cytologic sign of significantly poor prognosis. Cancer Cytopathol 2004;102:81-6 https://doi.org/10.1002/cncr.20125
  3. Kuroda N. Hamaguchi N. Ohara M. Intracytoplasmic lumina in invasive micropapillary carcinoma of the lung. Diagn Cytopathol 2006;34:224-6 https://doi.org/10.1002/dc.20427
  4. Duncan LD, Jacob S, Atkinson S. Fine needle aspiration cytologic findings of micropapillary carcinoma in the lung: a case report. Acta Cytol 2007;51:605-9 https://doi.org/10.1159/000325808
  5. Miyoshi T, Satoh Y, Okumura S, et al. Early-stage lung adenocarcinomas with a micropapillary pattern, a distinct pathologic marker for a significantly poor prognosis. Am J Surg Pathol 2003;27:101-9 https://doi.org/10.1097/00000478-200301000-00011