Journal of Biomedical Engineering Research (대한의용생체공학회:의공학회지)

The Korean Society of Medical and Biological Engineering (대한의용생체공학회)
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The Study of Mechanical Simulation for Human Respiratory System

인체 호흡 모사를 위한 기계적 장치 연구

  • Chi, S.H. (Department of Mechanical Engineering, Sogang University) ;
  • Lee, M.K. (Department of Mechanical Engineering, Sogang University) ;
  • Lee, T.S. (Department of Mechanical Engineering, Sogang University) ;
  • Choi, Y.S. (Oxus Co.) ;
  • Oh, S.K. (Oxus Co.)
  • Published : 2008.08.30
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Abstract

A patient with respiratory disorders such as a sleep apnea is increasing as the obese patient increase on the modern society. Positive Airway Pressure (PAP) devices are used in curing patient with respiratory disorders and turn out to be efficacious for patients of 75%. However, these devices are required for evaluating their performance to improve their performance by the mechanical breathing simulator. Recently, the mechanical breathing simulator was studied by the real time feedback control. However, the mechanical breathing simulator by an open loop control was specially required in order to analyze the effect of flow rate and pressure after operating the breathing auxiliary devices. Therefore the aims of this study were to make the mechanical breathing simulator by a piston motion and a valve function from the characteristic test of valve and motor, and to duplicate the flow rate and pressure profiles of some breathing patterns: normal and three disorder patterns. The mechanical simulator is composed cylinder, valve, ball screw and the motor. Also, the characteristic test of the motor and the valve were accomplished in order to define the relationship between the characteristics of simulator and the breathing profiles. Then, the flow rate and pressure profile of human breathing patterns were duplicated by the control of motor and valve. The result showed that the simulator reasonably duplicated the characteristics of human patterns: normal, obstructive sleep apnea (OSA), mild hypopnea with snore and mouth expiration patterns. However, we need to improve this simulator in detail and to validate this method for other patterns.

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References

  1. Fry, D. L., "A preliminary lung model for simulating the aerodynamics of the bronchial tree," In Computer and Biomedical Research 2, pp.111-134, 1968 https://doi.org/10.1016/0010-4809(68)90030-X
  2. Tilkian, A. G., Guilleminault, c., Schroeder, J. S., "Sleep-induced apnea syndrome: Prevalence of cardiac arrhythmias and their reversal after tracheostomy," Am J Med, 63:348, 1977 https://doi.org/10.1016/0002-9343(77)90272-8
  3. McArdle, N., Devereux, G., Heidamejad H., et al., "Long-term use of CP AP therapy for sleep apnea/hypopneas syndrome," Am J Respir Crit Care Med, 159: 1108-1114, 1999 https://doi.org/10.1164/ajrccm.159.4.9807111
  4. Verbraak, A. F. M., Rijnbeek, P.R., Beneken, J. E. W., Bogaard, J. M. and Versprille, A., "A new approach to mechanical simulation of lung behaviour: pressure-controlled and time-related piston movement," Med. Biol.Eng.Comput, Vol. 39, pp.82-89, 2001 https://doi.org/10.1007/BF02345270
  5. Smits, A. J., A Physical Introduction to Fluid Mechanics, New York: Wiley, 2000, pp.370-371
  6. Melo, P. L., Andrade Lemes, L, N, "Instrumentation for the Analysis of respiratory system disoders during sleep: Design and application," Rev. Sci. Instrum, Vol. 73, No. 11, pp.3926-3932, 2002 https://doi.org/10.1063/1.1511793
  7. Mesic, S., Babuska, R, Hoogsteden, H. C. and Verbraak, A. F. M., "Computer-controlled mechanical simulation of the artificially ventilated human respiratory system," IEEE Transactions on Biomedical Engineering June, Vol. 50, No.6, pp.731-743, 2003 https://doi.org/10.1109/TBME.2003.812166
  8. Rigau, J., Montserrat, J. M., Wohrle, H., Plattner, D., Schwaibold, M., Navajas, D. and Farre, R, "Bench model to simulate upper airway obstruction for analyzing automatic continuous positive airway pressure devices," Chest Journal August, Vol. 130, pp.350-361, 2006 https://doi.org/10.1378/chest.130.2.350
  9. S. I. Rubinow, "Introduction to Mathe matical Biology," New York: Academic Press, 1975