Korean Journal of Community Nutrition (대한지역사회영양학회지)

The Korean Society of Community Nutrition (대한지역사회영양학회)
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Blood Lipid Levels, Nutrient Intakes and Health-Related Lifestyles of Industrial Male Workers According to Apolipoprotein E Polymorphisms

Apolipoprotein E 다형성에 따른 사업장 근로자의 혈중 지질농도, 영양소 섭취 및 건강관련 생활습관

  • Park, Yoo-Kyoung (Department of Medical Nutrition, Graduate School of East-West Medical Science, Kyung Hee University) ;
  • Cho, Sang-Woon (Radiation Health Research Institute, Korea Hydro & Nuclear Power Co., Ltd) ;
  • Kang, Ji-Yeon (Radiation Health Research Institute, Korea Hydro & Nuclear Power Co., Ltd) ;
  • Paek, Yun-Mi (Radiation Health Research Institute, Korea Hydro & Nuclear Power Co., Ltd) ;
  • Sung, Sook-Hee (Radiation Health Research Institute, Korea Hydro & Nuclear Power Co., Ltd) ;
  • Choi, Tae-In (Radiation Health Research Institute, Korea Hydro & Nuclear Power Co., Ltd)
  • 박유경 (경희대학교 동서의학대학원 의학영양학과) ;
  • 조상운 (한국수력원자력(주) 방사선보건연구원) ;
  • 강지연 (한국수력원자력(주) 방사선보건연구원) ;
  • 백윤미 (한국수력원자력(주) 방사선보건연구원) ;
  • 성숙희 (한국수력원자력(주) 방사선보건연구원) ;
  • 최태인 (한국수력원자력(주) 방사선보건연구원)
  • Published : 2008.10.30
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Abstract

The purpose of this study was to investigate the association among nutrient intakes and health-related lifestyles with cardiovascular disease risk assessed by blood lipid profile according to Apolipoprotein E genotypes. Middle-aged industrial male workers who had completed their annual medical examination were recruited and data of 675 subjects who finished the nutrient survey were used in the analysis. Anthropometric parameters, dietary assessment (FFQ), health-related lifestyles and blood profiles were used for statistical analyses. Apo E genotype groups were classified into the following three genotypes: Apo E2 group (including E2/E2, E2/E3, E2/E4), Apo E3 group (including E3/E3), Apo E4 group (including E3/E4, E4/E4). The frequency of Apo E2, E3, and E4 allele were 13.3%, 75.0% and 11.7% respectively. There were no significant differences in the anthropometric parameters depending on different Apo E genotypes. Also, no significant differences in the nutrient intakes were found according to the genotype groups. The nutrient intakes of all subjects were similar to or higher than the level of KDRIs (Dietary Reference Intakes For Koreans) except for intakes of calcium (67.44% of KDRIs), vitamin A (73.83% of KDRIs) and vitamin $B_2$ (78.02% of KDRIs). Also, there were no significant differences of health-related lifestyles according to Apo E genotype groups. As for the lipid profiles, Apo E4 group had significantly higher total and LDL-cholesterol concentrations than the Apo E2 group (p < 0.05). We confirmed that plasma total and LDL-cholesterol concentrations were greatly influenced by Apo E genotypes. However, nutrient intakes and health-related lifestyles were not associated with Apo E genotypes.

Keywords

References

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