The Journal of Internal Korean Medicine (대한한방내과학회지)
- Volume 29 Issue 2
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- Pages.490-499
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- 2008
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- 1226-9174(pISSN)
Effects of Trichosanthes kirilowii Extract against Angiogenesis and Various Tumor Cells' Growth
천화분 추출물이 혈관신생 및 암세포성장에 미치는 영향
- Kim, Dong-Woo (Department of East-West Cancer Center, Oriental Hospital of Daejeon University) ;
- Lee, Jong-Hoon (Department of East-West Cancer Center, Oriental Hospital of Daejeon University) ;
- Yoo, Hwa-Seung (Department of East-West Cancer Center, Oriental Hospital of Daejeon University) ;
- Cho, Jung-Hyo (Department of East-West Cancer Center, Oriental Hospital of Daejeon University) ;
- Lee, Yeon-Weol (Department of East-West Cancer Center, Oriental Hospital of Daejeon University) ;
- Son, Chang-Gue (Department of East-West Cancer Center, Oriental Hospital of Daejeon University) ;
- Cho, Chong-Kwan (Department of East-West Cancer Center, Oriental Hospital of Daejeon University)
- 김동우 (대전대학교 동서암센터) ;
- 이종훈 (대전대학교 동서암센터) ;
- 유화승 (대전대학교 동서암센터) ;
- 조정효 (대전대학교 동서암센터) ;
- 이연월 (대전대학교 동서암센터) ;
- 손창규 (대전대학교 동서암센터) ;
- 조종관 (대전대학교 동서암센터)
- Published : 2008.06.30
Abstract
Objectives : This study was aimed to elucidate the effects of Trichosanthes kirilowii extract (TKE) on the angiogenesis and growth of tumor cells. Methods : Tube formation assay was performed by using human umbilical vein endothelial cells (HUVEC), and anchorage dependent colony assay was performed by using B16-F10 melanoma, Hep G2 and HT1080, CT-26 and SNU-1 cells. Results : For HUVEC, TKE at a level of more than 100