대한한방부인과학회지 (The Journal of Korean Obstetrics and Gynecology)
- 제21권3호
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- Pages.34-59
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- 2008
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- 1229-4292(pISSN)
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- 2508-3619(eISSN)
궁귀조혈음(芎歸調血飮)이 흰쥐의 자궁내막증 형성 억제에 미치는 영향
Inhibiting Effecposets of Gungguijohyeoleum on the Development of Experimentally-induced Endometriosis in the Rats
- 최변탁 (세명대학교 한의과대학 한방부인과교실) ;
- 서일복 (세명대학교 한의과대학 한방부인과교실) ;
- 이동녕 (세명대학교 한의과대학 한방부인과교실) ;
- 김형준 (세명대학교 한의과대학 한방부인과교실)
- Choi, Byun-Tak (Dept. of Oriental Gynecology, College of Oriental Medicine, Se-Myung University) ;
- Seo, Il-Bock (Dept. of Oriental Gynecology, College of Oriental Medicine, Se-Myung University) ;
- Lee, Dong-Nyung (Dept. of Oriental Gynecology, College of Oriental Medicine, Se-Myung University) ;
- Kim, Hyung-Jun (Dept. of Oriental Gynecology, College of Oriental Medicine, Se-Myung University)
- 발행 : 2008.08.30
초록
Purpose: This study was performed to investigate the inhibiting effects of Gungguijohyeoleum on the development of experimentally-induced endometriosis in rats. Methods: Endometriosis was induced in rats by autotransplanting uterine tissue to the peritoneum and we divided them into three groups: (1) sham-operated group(n=8), (2) surgically induced endometriosis and untreated control group(n=8), (3) surgically induced endometriosis and Gungguijohyeoleum treated group(n=8), Gungguijohyeoleum was orally administrated for 15 days after operation. Then we measured the body weight, the volumes of endometriotic implants, the weight of uterus and ovary, and investigated the concentrations of cytokines(MCP-1,