The Journal of Korean Obstetrics and Gynecology (대한한방부인과학회지)
- Volume 21 Issue 3
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- Pages.1-17
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- 2008
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- 1229-4292(pISSN)
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- 2508-3619(eISSN)
Effects of Scutellaria baicalensis on Surgically Induced Endometriosis in Rats after Oral or Rectal Administration
황분(黃芬)의 경구와 직장투여가 실험적으로 유발된 자궁내막증에 미치는 영향
- Lee, Hyun-Hee (Dept. of Gynecology, College of Oriental Medicine, Kyungwon University) ;
- Kim, Yoon-Sang (Dept. of Gynecology, College of Oriental Medicine, Kyungwon University) ;
- Lim, Eun-Mee (Dept. of Gynecology, College of Oriental Medicine, Kyungwon University)
- Published : 2008.08.30
Abstract
Purpose: Scutellaria baicalensis is a herb which has effect of eliminating heat, drying dampness, purging away fire, detoxicating. Clinically, has been used to remove fever and control of inflammation. We have studied in series to investigate the effective traditional oriental medicines of treatment for endometriosis. In this study, the effects of Scutellaria baicalensis administrated orally or rectally on surgically induced endometriosis in rat were investigated. Methods: The endometrial tissues of rats were autografted to their small intestine. Rats with surgically induced endometriosis were administered with Scutellaria baicalensis extracts for 40 days orally or rectally. We observed the tissue size of ectopic uterine implants at the mesenteric with the naked eye and examined the concentration of estradiol, progesterone,