대한본초학회지 (The Korea Journal of Herbology)
- 제23권2호
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- Pages.137-143
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- 2008
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- 1229-1765(pISSN)
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- 2288-7199(eISSN)
생약초 청국장이 흰쥐의 혈액성분 및 뇨에 미치는 영향
Effects of Herbal-cheonggukjang on Serum Composition and Urine in Rats
- 김형우 (산업용가속기이용 생물연구센터) ;
- 조수진 (고려대학교 의과대학) ;
-
김부여
(한국한의학연구원) ;
- 정선 (동신대학교 한의과대학) ;
-
박정숙
(광주여자대학교 대체요법학과) ;
-
이숙영
(조선대학교 단백질소재 연구센터) ;
- 조수인 (부산대학교 한의학전문대학원)
- Kim, Hyung-Woo (Research Center of Industrial Accelerators) ;
- Cho, Su-Jin (College of Medicine, Korea University) ;
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Kim, Bu-Yeo
(Korea Institute of Oriental Medicine) ;
- Jung, Sun (College of Korean Medicine, Dongshin University) ;
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Park, Jung-Suk
(Department of Complementary Alternative Therapy, Kwang-ju Womens University) ;
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Lee, Sook-Young
(Research Center for Proteineous Materials, Chosun University) ;
- Cho, Su-In (School of Oriental Medicine, Pusan National University)
- 발행 : 2008.06.30
초록
Objectives : Cheonggukjang(natto) is known to have anti-hyperlipidemic action in our previous study. This study was designed to investigate the safety of Prototype-cheonggukjang (PC, Herbal-natto). Methods : We investigated the effects of PC on changes in body weights, food uptake, water uptake, levels of AST/ALT, levels of BUN/creatinine and electrolytes in serum from normal mice. PC is made by cheonggukjang added Codonopsis Lanceolata, Houttuynia cordata and Lentinus edodes in indicated concetrations. Results : In this experiment, PC group showed equal levels of body weights, urine volume compared to non-treated control group. Oral administration of PC did not affect food and water uptake too. Levels of AST/ALT, which are markers of liver function, were not changed by administration of PC. In addition, levels of BUN/creatinine, which are markers of renal function, were not affected by PC too. Finally electrolytes in serum were not affected by PC. Conclusions : These results imply that oral administration of PC is safe in the framework of liver and renal function, and electrolytes in serum.