The Korea Journal of Herbology (대한본초학회지)
- Volume 23 Issue 2
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- Pages.51-58
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- 2008
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- 1229-1765(pISSN)
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- 2288-7199(eISSN)
Effects of Aqueous Extract from Lonicera Japonica Flower on Trimellitic Anhydride-induced Contact Hypersensitivity in BALB/c Mice
수용성 금은화 추출물이 Trimellitic Anhydride 유도 마우스 접촉성 과민반응에 미치는 영향
- Lee, Jung-No (Dept. of Bio Quality Control, Korea Bio Polytechnic) ;
- Jeong, Seung-Il (Jeonju Biomaterials Institute) ;
- Jang, Seon-Il (School of Alternative Medicine & Health Science, College of Alternative Medicine, Jeoniu University)
- Published : 2008.06.30
Abstract
Objectives : Trimellitic anhydride (TMA), a sensitizer that induces occupational asthma and atopic dermatitis, is widely used industrially to make epoxy and alkyd resins, plasticizers, high temperature polymer, and surfactants. The aim of this study was to investigative the effects of aqueous extracts of Lonicera japonica Flower(LJFAE) on TMA-induced contact hypersensitivity (CHS) in Balb/c mice. Methods : The dried flowers of L. japonica were extracted with distilled water at
Keywords
- Lonicera japonica Flower;
- IgE;
- Trimellitic anhydride;
- Th1/Th2 cytokines;
- Prostaglandin E2;
- Leukocytes;
- Contact hypersensitivity;
- Ear swelling responses