대한본초학회지 (The Korea Journal of Herbology)

  • 제23권3호
  • /
  • Pages.175-180
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  • 2008
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  • 1229-1765(pISSN)
  • /
  • 2288-7199(eISSN)
대한본초학회 (The Korea Association of Herbology)
권호 표지

연전초(連錢草) 추출물이 Streptozotocin으로 유발시킨 흰쥐의 당뇨에 미치는 영향

Antidiabetic Effect of Glechoma longituba (Nakai) Kupr in Diabetic Rats induced by Streptozotocin

  • 이경진 (경희대학교 한의과대학 본초학교실) ;
  • 함인혜 (경희대학교 한의과대학 본초학교실) ;
  • 부영민 (경희대학교 한의과대학 본초학교실) ;
  • 김호철 (경희대학교 한의과대학 본초학교실) ;
  • 최호영 (경희대학교 한의과대학 본초학교실)
  • Lee, Kyung-Jin (Dept. of Herbology, College of Oriental Medicine, Kyung Hee University) ;
  • Ham, In-Hye (Dept. of Herbology, College of Oriental Medicine, Kyung Hee University) ;
  • Bu, Young-Min (Dept. of Herbology, College of Oriental Medicine, Kyung Hee University) ;
  • Kim, Ho-Cheol (Dept. of Herbology, College of Oriental Medicine, Kyung Hee University) ;
  • Choi, Ho-Young (Dept. of Herbology, College of Oriental Medicine, Kyung Hee University)
  • 발행 : 2008.09.30
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초록

Objecitivies : While Glechoma longituba (Nakai) Kupr(GL) has been known as a antiinflammatory, antidiabetic and antihypertension medicine in korea traditional medicine, there has been only a few researches about it in Korea. Thus, we examined antidiabetic effect of GL in diabetic rats induced by streptozotocin Methods : To verify the effects of GL on serum glucose, creatinine, BUN, total cholesterol and triglyceride through streptozotocin-induced diabetic rats, some rats were injected 1 time with 55mg/kg streptozotocin intraperitoneally to induce diabetes, and other rats were injected with buffer I.P. as control group. Results : GL extracts significantly reduced the amount of serum glucose, BUN, creatinine, and triglyceride level in diabetics rats induced by streptozotocin. Conclusions : According to above result, Glechoma longituba was expected to be applied to the treatment of diabetes mellitus.

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