대한본초학회지 (The Korea Journal of Herbology)
- 제23권3호
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- Pages.127-134
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- 2008
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- 1229-1765(pISSN)
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- 2288-7199(eISSN)
LPS로 자극한 RAW264.7 세포에서 강활 추출물의 염증성세포활성물질의 억제효과
Inhibitory Effect of Extract from Ostericum koreanum on LPS-induced Proinflammatory Cytokines Production in RAW264.7 Cells
- 박희제 (원광대학교 한의과대학 본초학교실) ;
-
배기상
(원광대학교 한의과대학 본초학교실) ;
- 김도윤 (원광대학교 약학대학 한약학과) ;
- 서상완 (경희대학교 의과대학 미생물학교실) ;
- 박경배 (원광대학교 약학대학 한약학과) ;
- 김병진 (원광대학교 약학대학 한약학과) ;
- 송제문 (원광대학교 한의과대학 본초학교실) ;
- 이경용 (원광대학교 한의과대학 본초학교실) ;
- 나철 (원광대학교 한방병원 재활의학과) ;
- 신병철 (원광대학교 한방병원 재활의학과) ;
-
박성주
(원광대학교 한의과대학 본초학교실) ;
-
송호준
(원광대학교 한의과대학 본초학교실) ;
-
황성연
(원광대학교 한의과대학 본초학교실)
- Park, Hee-Je (Dept. of Herbology, College of Oriental Medicine, Wonkwang University) ;
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Bae, Gi-Sang
(Dept. of Herbology, College of Oriental Medicine, Wonkwang University) ;
- Kim, Do-Yun (Dept. of Oriental Pharmacy, College of Pharmacy, Wonkwang University) ;
- Seo, Sang-Wan (Dept. of Microbiology, College of Medicine, Kyung Hee University) ;
- Park, Kyung-Bae (Dept. of Oriental Pharmacy, College of Pharmacy, Wonkwang University) ;
- Kim, Byung-Jin (Dept. of Oriental Pharmacy, College of Pharmacy, Wonkwang University) ;
- Song, Je-Moon (Dept. of Herbology, College of Oriental Medicine, Wonkwang University) ;
- Lee, Kyung-Yong (Dept. of Herbology, College of Oriental Medicine, Wonkwang University) ;
- Na, Chul (Dept. of Oriental Rehabilitation Medicine, IKsan Wonkwang Oriental Hospital) ;
- Shin, Byung-Chul (Dept. of Oriental Rehabilitation Medicine, IKsan Wonkwang Oriental Hospital) ;
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Park, Sung-Joo
(Dept. of Herbology, College of Oriental Medicine, Wonkwang University) ;
-
Song, Ho-Joon
(Dept. of Herbology, College of Oriental Medicine, Wonkwang University) ;
-
Hwang, Sung-Yeon
(Dept. of Herbology, College of Oriental Medicine, Wonkwang University)
- 발행 : 2008.09.30
초록
Objectives : The present study was designed to investigate whether Ostericum koreanum (OK) could regulate lipopolysaccharide (LPS)-induced inflammatory response in vitro and in vivo. Methods : To evaluate of anti-inflammatory effect of OK, we examined Nitric oxide (NO), proinflammatory cytokines production in LPS-stimulated RAW264.7 cells. Furthermore, we checked molecular mechanism especially in the phosphorylation of mitogen-activated protein kinases (MAPKs) and the degradation of inhibitory kappa B a (