Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
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Stability test of the Extracts of Cimicifugae Rhizoma, Achyranthis Radix, Artemisia Capillaris Herba, Moutan Cortex Radicis and Arecae Semen for Toxicity Study

승마, 우슬, 인진호, 목단피 및 빈랑자의 독성연구를 위한 안정성 시험

  • Kim, Seung-Hyun (Institute for Life Science, Elcom Science Co. Ltd.) ;
  • Choi, Eun-Jung (Institute for Life Science, Elcom Science Co. Ltd.) ;
  • Kim, Dae-Hyun (Institute for Life Science, Elcom Science Co. Ltd.) ;
  • Lee, Ki-Yong (College of Pharmacy and Research Institute of Pharmaceutical Science, Seoul National University) ;
  • Lee, Min-A (College of Pharmacy and Research Institute of Pharmaceutical Science, Seoul National University) ;
  • Baek, Sa-Wang (College of Pharmacy and Research Institute of Pharmaceutical Science, Seoul National University) ;
  • Kwack, Seung-Jun (Department of Toxicological Research, National Institute of Toxicological Research) ;
  • Kang, Tae-Suk (Department of Toxicological Research, National Institute of Toxicological Research) ;
  • Kim, Young-Choong (College of Pharmacy and Research Institute of Pharmaceutical Science, Seoul National University) ;
  • Sung, Sang-Hyun (College of Pharmacy and Research Institute of Pharmaceutical Science, Seoul National University)
  • 김승현 ((주)엘컴사이언스 생명과학연구소) ;
  • 최은정 ((주)엘컴사이언스 생명과학연구소) ;
  • 김대현 ((주)엘컴사이언스 생명과학연구소) ;
  • 이기용 (서울대학교 약학대학) ;
  • 이민아 (서울대학교 약학대학) ;
  • 백사왕 (서울대학교 약학대학) ;
  • 곽승준 (국립독성과학원 독성연구부) ;
  • 강태석 (국립독성과학원 독성연구부) ;
  • 김영중 (서울대학교 약학대학) ;
  • 성상현 (서울대학교 약학대학)
  • Published : 2008.09.30
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Abstract

Quantitative methods for the marker compounds of Cimicifugae Rhizoma, Achyranthis Radix, Artemisiae Capillaris Herba, Moutan Cortex Radicis and Arecae Semen, respectively, were developed using HPLC-DAD. Using the established methods, each extract of the natural medicines were evaluated. In addition, long term and accelerated stability test in the extracts were examined for six months. No significant change in content of the marker compounds of each extract observed during the time of investigation.

Keywords

References

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