Tuberculosis and Respiratory Diseases

  • 제64권6호
  • /
  • Pages.451-455
  • /
  • 2008
  • /
  • 1738-3536(pISSN)
  • /
  • 2005-6184(eISSN)
대한결핵및호흡기학회 (The Korean Academy of Tuberculosis and Respiratory Diseases)
권호 표지

당뇨 환자에서 진단된 대량 객혈을 보인 폐 모균증 1예

A Case of Angio-invasive Pulmonary Mucormycosis with Uncontrolled Diabetes Mellitus

  • 조유지 (경상대학교 의과대학 전문대학원 내과학교실) ;
  • 강명희 (경상대학교 의과대학 전문대학원 내과학교실) ;
  • 김현식 (경상대학교 의과대학 전문대학원 내과학교실) ;
  • 정이영 (경상대학교 의과대학 전문대학원 내과학교실) ;
  • 장인석 (경상대학교 의과대학 전문대학원 흉부외과학교실) ;
  • 김호철 (경상대학교 의과대학 전문대학원 내과학교실) ;
  • 황영실 (경상대학교 의과대학 전문대학원 내과학교실) ;
  • 이종덕 (경상대학교 의과대학 전문대학원 내과학교실)
  • Cho, Yu Ji (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Gyeongsang National University College of Medicine) ;
  • Kang, Myoung Hee (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Gyeongsang National University College of Medicine) ;
  • Kim, Hyeon Sik (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Gyeongsang National University College of Medicine) ;
  • Jeong, Yi Yeong (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Gyeongsang National University College of Medicine) ;
  • Jang, In-Seok (Department of Thoracic and Cardiovascular Surgery, Gyeongsang National University College of Medicine) ;
  • Kim, Ho Cheol (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Gyeongsang National University College of Medicine) ;
  • Hwang, Young Sil (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Gyeongsang National University College of Medicine) ;
  • Lee, Jong Deog (Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Gyeongsang National University College of Medicine)
  • 투고 : 2008.05.02
  • 심사 : 2008.06.02
  • 발행 : 2008.06.30
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초록

저자들은 잘 조절되지 않는 당뇨병을 가진 75세 환자에서 혈관을 침범한 폐 모균증으로 인해 항진균제와 수술적 치료를 시행하였으나 진행되는 다발성 괴사로 인한 객혈로 사망한 폐 모균증 1예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

Pulmonary mucormycosis is an uncommon, serious opportunistic infection caused by fungi belonging to the order Mucorales and it occurs exclusively in debilitated or immuno-compromised hosts. It is known that the fungi can invade the blood vessels and cause serious ischemic necrosis and bleeding5. We experienced a fatal case of pulmonary mucormycosis in a diabetic 75-year-old man who developed a progressive necrotizing lesion despite administering proper and prompt medical and surgical treatment. We report here on this case along with a review of the relevant medical literature.

키워드

참고문헌

  1. Sugar AM. Mucormycosis. Clin Infect Dis 1992;14: S126-9 https://doi.org/10.1093/clinids/14.Supplement_1.S126
  2. Rinaldi MG. Zygomycosis. Infect Dis Clin North Am 1989;3:19-41
  3. Virally ML, Riveline JP, Virally J, Chevojon P, Regnard JF, Belmekki A, et al. Pulmonay mucormycosis in a diabetic patient with HIV. Diabetes Care 2002;25:2105 https://doi.org/10.2337/diacare.25.11.2105
  4. Joshi N, Caputo GM, Weitekamp MR, Karchmer AW. Infections in patients with diabetes mellitus. N Engl J Med 1999;341:1906-12 https://doi.org/10.1056/NEJM199912163412507
  5. Davies SF, Knox KS, Sarosi GA. Chapter 34. Fungal infection. In: Mason RJ, Broaddus VC, Murray JF, Nadel JA, editors. Murray and Nadel's textbook of respiratory medicine. 4th ed. Philadelphia: Sanders Elsevier Inc; 2005. p. 1073-4
  6. Murray HW. Pulmonary mucormycosis with massive fatal hemoptysis. Chest 1975;68:65-8 https://doi.org/10.1378/chest.68.1.65
  7. Ribes JA, Vanover-Sams CL, Baker DJ. Zygomycetes in human disease. Clin Microbiol Rev 2000;13:236-301 https://doi.org/10.1128/CMR.13.2.236-301.2000
  8. Chang MS, Woo JH. Opportunistic fungal infection. Hanyang Med Rev 2006;26:20-33
  9. McAdams HP, Rosado de Christenson M, Strollo DC, Patz EF Jr. Pulmonary mucormycosis: radiologic findings in 32 cases. AJR Am J Roentgenol 1997;168: 1541-8 https://doi.org/10.2214/ajr.168.6.9168721