참고문헌
- Johnson WM, Lior H. Response of Chinese hamster ovary cells to a cytolethal distending toxin (CDT) of Escherichia coli and possible misinterpretation as heat-labile (LT) enterotoxin. FEMS Microbial. Lett 1987;43:19-23. https://doi.org/10.1111/j.1574-6968.1987.tb02091.x
- Cortes-Bratti X, Frisan T, Thelestam M. The cytolethal distending toxins induce DNA damage and cell cycle arrest. Toxicon 2001;39:1729-1736. https://doi.org/10.1016/S0041-0101(01)00159-3
- Akifusa S, Poole S, Lewthwaite J, Henderson B, Nair SP. Recombinant Actinobacillus actinomycetemcomitans cytolethal distending toxin proteins are required to interact to inhibit human cell cycle progression and to stimulate human leukocyte cytokine synthesis. Infect Immun 2001;69: 5925-5930. https://doi.org/10.1128/IAI.69.9.5925-5930.2001
- Bang DD, Scheutz F, Ahrens P et al. Prevalence of cytolethal distending toxin (cdt) genes and CDT production in Campylobacter spp. isolated from Danish broilers. J Med Microbiol 2001;50:1087-1094. https://doi.org/10.1099/0022-1317-50-12-1087
- Saiki K, Konishi K, Gomi T, Nishihara T, Yoshikawa M. Reconstitution and purification of cytolethal distending toxin of Actinobacillus actinomycetemcomitans. Microbiol Immunol 2001;45:497-506. https://doi.org/10.1111/j.1348-0421.2001.tb02650.x
- Mayer MP, Bueno LC, Hansen EJ, DiRienzo JM. Identification of a cytolethal distending toxin gene locus and features of a virulence-associated region in Actinobacillus actinomycetemcomitans. Infect Immun 1999;67:1227-1237.
- Sugai M, Kawamoto T, Peres SY et al. The cell cycle-specific growth-inhibitory factor produced by Actinobacillus actinomycetemcomitans is a cytolethal distending toxin. Infect Immun 1998;66:5008-5019.
- Shenker BJ, Hoffmaster RH, McKay TL, Demuth DR. Expression of the cytolethal distending toxin (Cdt) operon in Actinobacillus actinomycetemcomitans: evidence that the CdtB protein is responsible for G2 arrest of the cell cycle in human T cells. J Immunol 2000;165:2612-2618. https://doi.org/10.4049/jimmunol.165.5.2612
- Mao X, DiRienzo JM. Functional studies of the recombinant subunits of a cytolethal distending holotoxin. Cell Microbiol 2002;4:245-255. https://doi.org/10.1046/j.1462-5822.2002.00186.x
- Mise K, Akifusa S, Watarai S et al. Involvement of ganglioside GM3 in G(2)/M cell cycle arrest of human monocytic cells induced by Actinobacillus actinomycetemcomitans cytolethal distending toxin. Infect Immun 2005;73:4846-4852. https://doi.org/10.1128/IAI.73.8.4846-4852.2005
- Kanno F, Korostoff J, Volgina A, DiRienzo JM. Resistance of human periodontal ligament fibroblasts to the cytolethal distending toxin of Actinobacillus actinomycetemcomitans. J Periodontol 2005;76:1189-1201. https://doi.org/10.1902/jop.2005.76.7.1189
- Lukasiewicz R. Analysis of the human periodontal ligament fibroblast response to the cytolethal distending toxin produced by Actinobacillus actinomycetemcomitans. Penn Dent J (Phila) 2001;101:6-7.
- Shenker BJ, Besack D, McKay T et al. Induction of cell cycle arrest in lymphocytes by Actinobacillus actinomycetemcomitans cytolethal distending toxin requires three subunits for maximum activity. J Immunol 2005;174:2228-2234. https://doi.org/10.4049/jimmunol.174.4.2228
- Shenker BJ, Demuth DR, Zekavat A. Exposure of lymphocytes to high doses of Actinobacillus actinomycetemcomitans cytolethal distending toxin induces rapid onset of apoptosis-mediated DNA fragmentation. Infect Immun 2006;74: 2080-2092. https://doi.org/10.1128/IAI.74.4.2080-2092.2006
- Frisk A, Lebens M, Johansson C et al. The role of different protein components from the Haemophilus ducreyi cytolethal distending toxin in the generation of cell toxicity. Microb Pathog 2001;30:313-324. https://doi.org/10.1006/mpat.2000.0436
- Cope LD, Lumbley S, Latimer JL et al. A diffusible cytotoxin of Haemophilus ducreyi. Proc Natl Acad Sci USA 1997;94:4056-4061.
- Lagergard T, Lundqvist A, Wising C, Gabrielsson V, Ahlman K. Formaldehyde treatment increases the immunogenicity and decreases the toxicity of Haemophilus ducreyi cytolethal distending toxin. Vaccine 2007;25:3606-3614. https://doi.org/10.1016/j.vaccine.2007.01.061
- Jarma E, Regassa LB. Growth phase mediated regulation of the Actinobacillus pleuropneumoniae ApxI and ApxII toxins. Microb Pathog 2004;36:197-203. https://doi.org/10.1016/j.micpath.2003.11.005
- Zambon JJ, Slots J, Genco RJ. Serology of oral Actinobacillus actinomycetemcomitans and serotype distribution in human periodontal disease. Infect Immun 1983;41:19-27.
- Nishikubo S, Ohara M, Ueno Y et al. An N-terminal segment of the active component of the bacterial genotoxin cytolethal distending toxin B (CDTB) directs CDTB into the nucleus. J Biol Chem 2003;278:50671-50681. https://doi.org/10.1074/jbc.M305062200
- Boesze-Battaglia K, Besack D, McKay T et al. Cholesterol-rich membrane microdomains mediate cell cycle arrest induced by Actinobacillus actinomycetemcomitans cytolethal-distending toxin. Cell Microbiol 2006;8:823-836. https://doi.org/10.1111/j.1462-5822.2005.00669.x
- Purven M, Frisk A, Lonnroth I, Lagergard T. Purification and identification of Haemophilus ducreyi cytotoxin by use of a neutralizing monoclonal antibody. Infect Immun 1997;65:3496-3499.
- Fong KP, Chung WO, Lamont RJ, Demuth DR. Intra- and interspecies regulation of gene expression by Actinobacillus actinomycetemcomitans LuxS. Infect Immun 2001;69:7625-7634. https://doi.org/10.1128/IAI.69.12.7625-7634.2001
- Belibasakis GN, Mattsson A, Wang Y, Chen C, Johansson A. Cell cycle arrest of human gingival fibroblasts and periodontal ligament cells by Actinobacillus actinomycetemcomitans: involvement of the cytolethal distending toxin. Apmis 2004;112:674-685. https://doi.org/10.1111/j.1600-0463.2004.apm1121006.x