Journal of Periodontal and Implant Science

  • 제38권1호
  • /
  • Pages.31-40
  • /
  • 2008
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  • 2093-2278(pISSN)
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  • 2093-2286(eISSN)
대한치주과학회 (Korean Academy of Periodontology)
권호 표지

한국 영아로부터 분리한 Enterococcus faecium의 구강 병원균에 대한 억제 효과

Inhibitory effects of Enterococcus faecium isolated from Korean infants on oral pathogens

  • 정은경 (원광대학교 치과대학 치주과학교실) ;
  • 이종철 (원광대학교 치과대학 치주과학교실) ;
  • 서정윤 (원광대학교 치과대학 치주과학교실) ;
  • 김성윤 (원광대학교 치과대학 치주과학교실) ;
  • 김완수 (원광대학교 치과대학 치주과학교실) ;
  • 윤우혁 (원광대학교 치과대학 치주과학교실) ;
  • 김윤상 (원광대학교 치과대학 치주과학교실) ;
  • 피성희 (원광대학교 치과대학 치주과학교실) ;
  • 유형근 (원광대학교 치과대학 치주과학교실) ;
  • 신형식 (원광대학교 치과대학 치주과학교실)
  • Jeong, Eun-Gyeong (Department of Periodontology, School of Dentistry, Wonkwang University) ;
  • Lee, Jong-Cheol (Department of Periodontology, School of Dentistry, Wonkwang University) ;
  • Seo, Jung-Yoon (Department of Periodontology, School of Dentistry, Wonkwang University) ;
  • Kim, Seong-Yoon (Department of Periodontology, School of Dentistry, Wonkwang University) ;
  • Kim, Wan-Su (Department of Periodontology, School of Dentistry, Wonkwang University) ;
  • Yun, Woo-Hyuk (Department of Periodontology, School of Dentistry, Wonkwang University) ;
  • Kim, Yun-Sang (Department of Periodontology, School of Dentistry, Wonkwang University) ;
  • Pi, Sung-Hee (Department of Periodontology, School of Dentistry, Wonkwang University) ;
  • You, Hyung-Keun (Department of Periodontology, School of Dentistry, Wonkwang University) ;
  • Shin, Hyung-Shik (Department of Periodontology, School of Dentistry, Wonkwang University)
  • 발행 : 2008.03.31
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초록

Purpose: The probiotic effects of lactic acid bacteria have widely been researched in diverse human pathogens, but only a few effects are reported against oral pathogens. The antimicrobial effects of the Enterococcus faecium 7413 isolated from Korean infants on the 9 pathogen including 6 oral streptococci were investigated the clinical use of the antimicrobial peptide for oral microflora control. Materials and Methods: E. faecium 7413 was identified by morphological, biochemical tests and 16S rDNA sequence analysis. Inhibitory effects of culture supernatants were determined for their ability to grow on agar plate containing pathogenic bacteria. Result: The culture supernatant of Enterococcus faecium 7413 showed inhibitory effects on oral pathogens, namely Streptococcus pyogenes KCTC 3556, S. pneumoniae KCTC 5080, S. mutans ATCC 25175, S. anginosus ATCC 33397, S. constellatus KCTC 3268, S. intermedius ATCC 27823 and Shigella flexneri KCTC 2008. Whereas it did not affect the multiplication of E. coli strains, KCTC 1041 and ATCC 43894. Conclusion: The data obtained in this study could be useful for future development of effective probiotics allowing prevention for oral pathogens.

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