Effects of Slander Glasswort (Salicornia herbacea L.) Extract on Improvements in Bowel Function and Constipation Relief

함초 추출물의 장 기능 개선과 변비 해소 효과

  • Cho, Young-Sim (Department of Food and Nutrition, Sookmyung Women's University) ;
  • ;
  • Han, Young-Sil (Department of Food and Nutrition, Sookmyung Women's University)
  • 조영심 (숙명여자대학교 식품영양학과) ;
  • 김순임 (숙명여자대학교 나노 바이오 소재센터) ;
  • 한영실 (숙명여자대학교 식품영양학과)
  • Published : 2008.06.30

Abstract

This study investigated the effects of dietary slander glasswort extract on improvements in bowel function and constipation relief. Balb/C mice were used to measure transit movement of a charcoal meal after slander glasswort extract was added to their drinking water at 0.36, 0.72, and 1.5 mg/mL concentrations. The extract's constipation relief effects were investigated in Sprague-Dawley rats with loperamide-induced constipation by adding 2, 3, and 4 mg/mL of the extract to their drinking water, and by feeding yogurt containing 0.0, 0.25, and 0.50% slander glasswort extract mixed into a 10-fold amount of water. The mice receiving the extract at 1.5 mg/mL via drinking water had a 16.4% increase in the rate of transit as compared to the controls. In addition, the rats receiving the extract via drinking water and yogurt had increased in constipation relief from 128 to 156% and from 107 to 150%, respectively, as compared to the controls. Based on the results, slander glasswort is considered to have effects on improving bowel function and relieving constipation.

함초 추출물의 장내 이동 효과를 살펴보기 위하여 함초 추출물을 식수에 첨가하여 장 이동률을 살펴본 결과 대조군에 비해 함초 추출물을 처리한 군에서 활성탄 식이의 장 이동률은 8.5-16.4% 증가되었다. 함초 추출물의 변비해소효과는 함초 추출물을 식수에 녹여 공급한 결과 대조군에 비해 함초 추출물을 3 mg/mL 처리한 군에서의 변량이 식수 섭취량과 관련하여 최대 156% 증가하였다. 또한 함초 요구르트의 변비해소효과는 0.25% 함초 요구르트의 공급으로 변비 유발기간 내 변량이 최대 150% 증가되었으며 처리군에 비해 loperamide를 계속 섭취함에도 불구하고 변비가 해소되었음을 알 수 있었다. 이상의 결과로 볼 때 함초 추출물은 장 이동률을 증가시켜 장운동을 촉진할 수 있으리라 생각되며 또한 변비 해소작용까지 나타내어 장 기능 개선에 효과를 나타내는 물질이라 생각된다.

Keywords

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