Textile Coloration and Finishing (한국염색가공학회지)

The Korean Society of Dyers and Finishers (한국염색가공학회)
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Antimicrobial Agents and Applications on Polymeric Materials

고분자재료에 대한 항균성 물질과 적용

  • Lee, Jae-Woong (Industrial Materials Research Institute, Kolon Industries, Inc.)
  • 이재웅 (㈜코오롱 중앙기술원 산자연구소)
  • Published : 2008.06.27
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Abstract

A wide variety of materials including aldehydes, cationic agents, alcohols, peroxygens, phenols and chlorinated phenols, metal ions are being employed as biocides. Among three levels for biocidal functions (sanitization, disinfection and sterilization), disinfection is an enough level for antimicrobial textiles. In terms of antimicrobial agents for textile applications, quaternary ammonium salts (QAS), chitosan, metal and metal salts, N-halamine based materials are developed with numerous research and the positive ions of those materials may result in disinfection of microorganisms. Photocatalysts, especially titanium dioxide (titania) produces the hydroxyl radical (${\cdot}\;OH$) which causes inactivation of microorganisms after UV radiation, have been used for antimicrobial applications.

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References

  1. W. A. Rutala and APIC Guidelines Committee, APIC guideline for selection and use of disinfectants, Am. J. Infect. Control, 24(4), 313-342(1996)
  2. S. S. Block, "Disinfection, Sterilization and Preservation (3rd ed.)", Lea & Febiger, Philadelphia, pp.469-492, 1983
  3. N. Philip, B. Saoudi, M. C. Crevier, M. Moisan, J. Barbeau and J. Pelletier, The respective roles of UV photons and oxygen atoms in plasma sterilization at reduced gas pressure: The case of $N_2-O_2$ mixtures, IEEE Transactions on Plasma Science, 30(4), 1429-1436(2002) https://doi.org/10.1109/TPS.2002.804203
  4. T. Akitsu, H. Ohkawa, M. Tsuji, H. Kimura and M. Kogoma, Plasma sterilization using glow discharge at atmospheric pressure, Surface & Coating Technology, 193, 29-34(2005) https://doi.org/10.1016/j.surfcoat.2004.07.042
  5. J. S. Chapman, Characterizing bacterial resistance to preservatives and disinfectants, Int. Biodeterior. Biodegrad., 41(3-4), 241-245(1998) https://doi.org/10.1016/S0964-8305(98)00025-0
  6. S. S. Block, "Disinfection, Sterilization and Preservation (3rd ed.)", Lea & Febiger, Philadelphia, pp.3-46, 1983
  7. E. Roelofsen, M. V. Leeuwen, G. J. Meijer- Severs and M. H. F. Wilkinson, Evaluation of the Effects of Storage in Two Different Swab Fabrics and under Three Different Transport Conditions on Recovery of Aerobic and Anaerobic Bacteria, J. Clin. Microbiol., 37, 3041-3043(1999)
  8. A. D. Russell, Bacterial spores and chemical sporicidal agents, Clinical Microbiology Reviews, 3(2), 99-199(1990) https://doi.org/10.1128/CMR.3.2.99
  9. S. P. Denyer and G. S. A. B. Stewart, Mechanisms of action of disinfectants, Int. Biodeterior. Biodegrad., 41, 261-268(1998) https://doi.org/10.1016/S0964-8305(98)00023-7
  10. T. E. Cloete, Resistance mechanisms of bacteria to antimicrobial compounds, Int. Biodeterior. Biodegrad., 51, 277-282(2003) https://doi.org/10.1016/S0964-8305(03)00042-8
  11. R. M. E. Richards, D. K. L. Xing and T. P. King, Activity of p-aminobenzoic acid compared with other organic acids against selected bacteria, J. Appl. Bacteriol., 78, 209-215(1995) https://doi.org/10.1111/j.1365-2672.1995.tb05018.x
  12. S. P. Denyer, Mechanisms of action of antibacterial biocides, Int. Biodeterior. Biodegrad., 36, 227-245(1995) https://doi.org/10.1016/0964-8305(96)00015-7
  13. J. Y. Maillard, Bacterial target sites for biocide action, Journal of Applied Microbiology Symposium Supplement, 92, 16-27(2002) https://doi.org/10.1046/j.1365-2672.92.5s1.3.x
  14. A. D. Russell, Assessment of sporicidal efficacy, Int. Biodeterior. Biodegrad., 41, 281-287(1998) https://doi.org/10.1016/S0964-8305(98)00019-5
  15. B. R. Kim, E. Anderson, S. A. Mueller, W. A. Gaines and A. M. kendall, Literature reviewefficacy of various disinfectants against Legionella in water systems, Water Research, 36, 4433-4444(2002) https://doi.org/10.1016/S0043-1354(02)00188-4
  16. J. S. Chapman, Disinfectant resistance mechanisms, cross-resistance, and co-resistance, Int. Biodeterior. Biodegrad., 51, 271-276(2003) https://doi.org/10.1016/S0964-8305(03)00044-1
  17. S. S. Block, "Disinfection, Sterilization and Preservation (3rd ed.)", Lea & Febiger, Philadelphia, pp.157-413, 1983
  18. C. Simons, S. E. Walsh, J. Y. Maillard et al. A note: Ortho-phthalaldehyde: proposed mechanism of action of a new antimicrobial agent, Lett. Appl. Microbiol., 31, 299-302(2000) https://doi.org/10.1046/j.1472-765x.2000.00817.x
  19. S. E. Walsh, J. Y. Malillard and A. D. Russell, Ortho-phthalaldehyde: a possible alternative to glutaraldehyde for high level disinfection, Journal of Applied Microbiology, 87, 702-710 (1999) https://doi.org/10.1046/j.1365-2672.1999.00913.x
  20. A. D. Russell and I. Chopra, "Understanding Antibacterial Action and Resistance (2nd ed)", Ellis Horwood, Chichester, UK, 1996
  21. A. D. Russell, Introduction of biocides into clinical practice and the impact on antibioticresistant bacteria, Journal of Applied Microbiology Symposium Supplement, 92, 121-135 (2002) https://doi.org/10.1046/j.1365-2672.92.5s1.12.x
  22. P. Broxton, P. M. Woodcock, F. Heatley et al., Interaction of some polyhexamethylene biguanides and membrane phospholipids in Escherichia coli, J. Appl. Bacteriol., 57, 115-124(1984) https://doi.org/10.1111/j.1365-2672.1984.tb02363.x
  23. G. Sauvet, W. Fortunlak, K. Kazmierski and J. Chojnowski, Amphiphilic block and statistical siloxane copolymers with antimicrobial activity, J. Polym. Sci., Part A: Polym. Chem., 41(19), 2939-2948(2003) https://doi.org/10.1002/pola.10895
  24. J. T. Holah, J. H. Taylor, D. J. Dawson and K. E. Hall, Biocide use in the food industry and the disinfectant resistance of persistent strains of Listeria monocytogenes and Escherichia coli, Journal of Applied Microbiology Symposium Supplement, 92, 111-120(2002) https://doi.org/10.1046/j.1365-2672.92.5s1.18.x
  25. G. Mcdonnell and A. D. Russell, Antiseptics and disinfectants: activity, action and resistance, Clinical Microbiology Reviews, 12, 147-179(1999)
  26. S. S. Block, "Disinfection, Sterilization and Preservation (5th ed.)", Lippincott Williams & Wilkins, Philadelphia, pp.185-204, 2001
  27. S. S. Block, "Disinfection, Sterilization and Preservation (3rd ed.)", Lea & Febiger, Philadelphia, pp.225-239, 1983
  28. S. S. Block, "Disinfection, Sterilization and Preservation (5th ed.)", Lippincott Williams & Wilkins, Philadelphia, pp.205-214, 2001
  29. X.-Z. Li, H. Nikaido and K. E. Williams, Silver-resistant mutants of Escherichia coli display active efflux of Ag+ and are deficient in porins, J. Bacteriol, 179, 6127-6132(1997) https://doi.org/10.1128/jb.179.19.6127-6132.1997
  30. T. Griebe, C. I. Chen, R. Srinivasan, G. G. Geesy and P. S. Stewart, Analysis of biofilm disinfection by monochloramine and free chlorine, "In Proceedings of the Center for Biofilm Engineering", Montana State University, Bozeman, pp.151-161, 1994
  31. D. E. Green and P. K. Stumpf, The mode of action of chlorine, J. Am. Water Works Assoc., 38, 1301-1305(1946)
  32. T. A. Bellar, J. J. Lichtenberg, R. C. Kroner, Occurrence of organohalides in chlorinated drinking waters, J. Am. Water Works Assoc., 66(12), 703-706(1974) https://doi.org/10.1002/j.1551-8833.1974.tb02129.x
  33. J. J. Rook, Formation of haloforms during chlorination of natural waters, Water Treatment and Examination, 23, 234-243(1974)
  34. National Academy of science, "Drinking water and Health (Vol. 7), Disinfectants and Disinfection By-Products", National Academy Press, Washington D. C., 1987
  35. R. L. Wolfe, N. R. Ward and B. H. Olson, Inorganic chloramines as drinking water disinfectants: a review, J. Am. Water Works Assoc., 76, 74-88(1984)
  36. S. D. Worley and D. E. Williams, Halamine water disinfectants, CRC Critical review in Environment Control, 18(2), 133-175(1988) https://doi.org/10.1080/10643388809388345
  37. K. A. Fitzgerald, A. Davies and A. D. Ressell, Uptake of ^{14}C-chlorhexidine$ diacetate to Escherichia coli and Pseudomonas aeruginosa and it reversal by azoletin, FEMS Microbiol. Lett., 60, 327-332(1989) https://doi.org/10.1111/j.1574-6968.1989.tb03495.x
  38. L. Qian and G. Sun, Durable and Regenerable Antimicrobial Textiles: Synthesis and Applications of 3-methylol-2,2,5,5-tetramethylimidazolidin-4-one (MTMIO), J. Appl. Polym. Sci., 89, 2418-2425(2003) https://doi.org/10.1002/app.12405
  39. S. D. Worley, W. B. Wheatley, H. H. Kohl, H. D. Burkett, J. H. Faison, J. A.VanHoose, and N. Bodor, "A Novel Bactericidal Agent for Treatment of Water, Water Chlorination: Environmental Impact and Health Effects" (Vol.4), ed. R.L.Jolley, pp.1105-1113, 1982
  40. S. D. Worley, W. B. Wheatley, H. H. Kohl, J. A. Van Hoose, H. D. Burkett, and N. Bodor, The Stability in Water of a New Chloramine Disinfectant, Water Res. Bull., 19, 97-100(1983) https://doi.org/10.1111/j.1752-1688.1983.tb04563.x
  41. J. Liang, R. Wu, J.-W. Wang, K. Barnes, S. D. Worley, U. Cho, J. Lee, R. M. Broughton and T.-S. Huang, N -halamine biocidal coatings, J. Ind. Microbiol. Biotechnol., 34, 157-163(2007) https://doi.org/10.1007/s10295-006-0181-5
  42. L. W. Hedgecock, "Antimicrobial Agents", Lee and Febiger, 1967
  43. W. Paulus, "Microbiocides for the Protection of Materials", Chapman and Hall, London, p.434, 1993
  44. A. D. Russell and N. J. Russell, "Fifty Years of Antimicrobials: Past Perspectives and Future Trends", Cambridge University Press, Cambridge, England, pp.327-365, 1995
  45. J. T. Marsh, "An Introduction to Textile Finishing", Chapman and Hall, London, pp. 507-524, 1966
  46. Hamlin, Mary, Finishes For Cellulosic Textiles Giving Permanent Protection against Microbiological Attack-A Survey of the Literature, Journal of the Textile Institute, 44(11), 745-753(1953) https://doi.org/10.1080/19447015308687892
  47. T. K. Kim and Y. Son, Effect of Reactive Anionic Agent on Dyeing of Cellulosic Fibers with a Berberine Colorant - part 2: Anionic Agent Treatment and Antimicrobial Activity of a Berberine Dyeing, Dyes and Pigments, 64(1), 85-89(2005) https://doi.org/10.1016/j.dyepig.2004.04.007
  48. T. K. Kim, S. H. Yoon and Y. Son, Effect of Reactive Anionic Agent on Dyeing of Cellulosic Fibers with a Berberine Colorant, Dyes and Pigments, 60(2), 121-127(2004) https://doi.org/10.1016/S0143-7208(03)00147-5
  49. M. Ma, Y. Sun and G. Sun, Antimicrobial Cationic Dyes, part 1: Synthesis and Characterization, Dyes and Pigments, 58(1), 27-35 (2003) https://doi.org/10.1016/S0143-7208(03)00025-1
  50. M. Ma and G. Sun, Antimicrobial Cationic Dyes, Part 3: Simultaneous Dyeing and Antimicrobial Finishing of Acrylic Fabrics, Dyes and Pigments, 66(1), 33-41(2005) https://doi.org/10.1016/j.dyepig.2004.09.001
  51. Y. H. Kim and G. Sun, Durable Antimicrobial Finishing of Nylon Fabrics with Acid Dyes and a Quaternary Ammonium Salt, Textile Research Journal, 71(4), 318-323(2001) https://doi.org/10.1177/004051750107100407
  52. Y. H. Kim and G. Sun, Dye Molecules as Bridges for Functional Modifications of Nylon: Antimicrobial Functions, Textile Research Journal, 70(8), 728-733(2000) https://doi.org/10.1177/004051750007000811
  53. Y. Son and G. Sun, Durable Antimicrobial Nylon 66 Fabric: Ionic Interactions with Quaternary Ammonium Salts, J. Appl. Polym. Sci., 90, 2194-2199(2003) https://doi.org/10.1002/app.12876
  54. P. Zhu and G. Sun, Antimicrobial Finishing of Wool Fabrics Using Quaternary Ammonium Salts, J. Appl. Polym. Sci., 93(3), 1037-1041(2004) https://doi.org/10.1002/app.20563
  55. M. Diz, M. R, Infante, P. Erra and A. Manresa, Antimicrobial Activity of Wool Treated with a New Thiol Cationic Surfactant, Textile Research Journal, 71(8), 695-700(2001) https://doi.org/10.1177/004051750107100808
  56. Y. Shin, D. I. Yoo and J. Jang, Molecular Weight Effect on Antimicrobial Activity of Chitosan Treated Cotton Fabrics, J. Appl. Polym. Sci., 80(13), 2495-2501(2001) https://doi.org/10.1002/app.1357
  57. K. F. El-Tahlawy, M. A. El-Bendary, A. G. Elhendawy and S. M. Hudson, The Antimicrobial Activity of Cotton Fabrics Treated with Different Crosslinking Agents and Chitosan, Carbohydrate Polymers, 60(4), 421-430(2005) https://doi.org/10.1016/j.carbpol.2005.02.019
  58. J. W. Lee, C. W. Nam, H. S. Seong and S. W. Ko, Antimicrobial Finish of Cotton Fabric with Chito-Oligosaccharide (I), Treatment onto Cotton Fabric by DMDHEU, Journal of the Korean Fiber Society, 35(10), 649-655(1998)
  59. Y. S. Chung, K. K. Lee and J. W. Kim, Durable Press and Antimicrobial Finishing of Cotton Fabrics with a Citric Acid and Chitosan Treatment, Textile Research Journal, 68(10), 772-775(1998) https://doi.org/10.1177/004051759806801011
  60. Y. H. Kim, C. W. Nam, J. W. Choi and J. Jang, Durable Antimicrobial Treatment of Cotton Fabrics Using N-(2-hydroxy)propyl-3- trimethylammonium Chitosan Chloride and Polycarboxylic Acids, J. Appl. Polym. Sci., 88(6), 1567-1572(2003) https://doi.org/10.1002/app.11845
  61. K. W. Oh, C. S. Kim and H. M. Choi, Application of Silane-Chitosan Mixed Solution to Cotton Finishing (I), Journal of the Korean Fiber Society, 34(12), 822-829(1997)
  62. S. H. Lim and S. M. Hudson, Application of a Fiber-Reactive Chitosan Derivative to Cotton Fabric as an Antimicrobial Textile Finish, Carbohydrate Polymers, 56(2), 227-234 (2004) https://doi.org/10.1016/j.carbpol.2004.02.005
  63. J. Y. Kim, Y. S. Chung and J. W. Kim, Preparation of Chitosan Derivative with Cyanuric Chloride and Antimicrobial Finishing Treatment of Cotton Fabric, Journal of the Korean Fiber Society, 36(8), 618-623(1999)
  64. H. H. Lim, C. W. Nam and S. W. Ko, Spinning and Properties of Cellulose/Chitosan Blend Fiber, Journal of the Korean Fiber Society, 34(7), 444-450(1997)
  65. S. S. Block, "Disinfection, Sterilization and Preservation (3rd ed.)", Lea & Febiger, Philadelphia, pp.390-400, 1983
  66. J. Scholz, G. Nocke, F. Hollstein and A. Weissbach, Investigations on Fabrics Coated with Precious Metals Using The Magnetron Sputter Technique with Regard to Their Antimicrobial Properties, Surface and Coatings Technology, 192(2-3), 252-256(2005) https://doi.org/10.1016/j.surfcoat.2004.05.036
  67. T. Arai, G. Freddi, G. M. Colonna, E. Scotti, A. Boschi, R. Murakami and M. Tsukada, Absorption of Metal Cations by Modified B. Mori Silk and Preparation of Fabrics with Antimicrobial Activity, J. Appl. Polym. Sci., 80(2), 297-303(2001) https://doi.org/10.1002/1097-4628(20010411)80:2<297::AID-APP1099>3.0.CO;2-Z
  68. T. Nakashima, Y. Sakagami and M. Matsuo, Antibacterial Efficacy of Cotton Fabrics Chemically Modified by Metal Salts, Biocontrol Science, 6(1), 9-15(2001) https://doi.org/10.4265/bio.6.9
  69. T. Yuranova, A. G. Rincon, A. Bozzi, S. Parra, C. Pulgarin, P. Albers and J. Kiwi, Antibacterial Textiles Prepared by RF-Plasma and Vacuum-UV Mediated Deposition of Silver, Journal of Photochemistry and Photobiology, A: Chemistry, 161(1), 27-34(2003) https://doi.org/10.1016/S1010-6030(03)00204-1
  70. Z. G. Hu, W. L. Chan, K. W. Chan and Y. S. Szeto, New Preparation of Chitosan/Silver Nanocomposite and Its Antibacterial Activity on Cotton, Polymer Preprints (American Chemical Society, Division of Polymer Chemistry), 46(2), 767-768(2005)
  71. S. H. Jeong, Y. H. Hwang and S. C. Yi, Antibacterial Properties of Padded PP/PE Nonwovens Incorporating Nano-Sized Silver Colloids, Journal of Materials Science, 40(20), 5413-5418(2005) https://doi.org/10.1007/s10853-005-4340-2
  72. S. Y. Yeo, H. J. Lee, and S. H. Jeong, Preparation of Nanocomposite Fibers for Permanent Antibacterial Effect, Journal of Materials Science, 38(10), 2143-2147(2003) https://doi.org/10.1023/A:1023767828656
  73. L. Zhang, L. Peng and Z. Su, Photocatalysis Anatase Thin Film Coated PAN Fibers Prepared at Low Temperature, Materials Chemistry and Physics, 98(1), 111-115(2006) https://doi.org/10.1016/j.matchemphys.2005.08.071
  74. N. Y. Liang and L. F. Chang, Fabricating Photocatalytic Antibacterial Polyester Grains and Textiles, U.S. Pat. 2006024228(2006)
  75. T. Takahashi, Y. Shoji, O. Inoue, Y. Miyamoto and K. Tokuda, Antibacterial Properties of Rayon Fibers Containing Titanium Oxide Photocatalyst, Biocontrol Science, 9(3), 51-60 (2004) https://doi.org/10.4265/bio.9.51
  76. G. Sun and X. Xu, Durable and Regenerable Antibacterial Finishing of Fabrics: Biocidal Properties, Text. Chem. Colorist, 30, 26-30 (1998)
  77. D. E. Williams, L. J. Swango, G. R. Wilt and S. D. Worley, Effect of Organic N-halamines on Selected Membrane Functions in Intact Staphylococcus Aureus Cells, Appl. Environ. Microbiol, 54, 1121-1127(1991)
  78. J. J. Kaminski, N. Bodor and T. Higuchi, N-Halo Derivatives III: Stabilization of Nitrogen- Chlorine Bond in N-Chloroamino Acid Derivatives, J. Pharm. Sci., 65, 553-557(1976) https://doi.org/10.1002/jps.2600650418
  79. G. Sun, X. Xu, J. R. Bickett and J. F. Williams, Durable and Regenerable Antibacterial Finishing of Fabrics with a New Hydantoin Derivative, Ind. Eng. Chem. Res., 40(4), 1016-1021(2001) https://doi.org/10.1021/ie000657t
  80. L. Qian and G. Sun, Durable and Regenerable Antimicrobial Textiles: Synthesis and Applications of 3-Methylol-2,2,5,5-Tetramethyl-Imidazolidin- 4-One (MTMIO), J. Appl. Polym. Sci., 89(9), 2418-2425(2003) https://doi.org/10.1002/app.12405
  81. G. Sun and X. Xu, Durable and Regenerable Antibacterial Finishing of Fabrics: Chemical Structures, Text. Chem. Colorist, 31(5), 31-35 (1999)
  82. K. Barnes, J. Liang, S. D. Worley, J. Lee, R. M. Broughton and T. S. Huang, Synthesis and Antimicrobial Applications of 5,5-Ethylenebis [5-Methyl-3-(3-Triethoxysilylpropyl) hydantoin, Biomaterials, 27, 4825-4830(2006) https://doi.org/10.1016/j.biomaterials.2006.05.023
  83. J. Liang, K. Barnes, Y. Chen, S. D. Worley, J. Lee, R. M. Broughton and T. S. Huang, Improved Antimicrobial Siloxane, Ind. Eng. Chem. Res., 46, 1861-1866(2007) https://doi.org/10.1021/ie061583+
  84. Y. Sun and G. Sun, Novel Regenerable N-halamine Polymeric Biocides. II. Grafting Hydantoin-Containing Monomers onto Cotton Cellulose, J. Appl. Polym. Sci., 81(3), 617-624 (2001) https://doi.org/10.1002/app.1477
  85. S. Liu and G. Sun, "Acyclic N-halamine Structures in Antibacterial Modification of Cotton, Abstracts of Papers", 231st ACS National Meeting, Atlanta, GA, United States, March 26-30, 2006
  86. J. Lee, R. M. Broughton, A. Akdag, S. D. Worley and T. S. Huang, Preparation and Application of an s-Triazine-Based Novel N-Halmine Biocide for Antimicrobial Fibers, Fibers and Polymers, 8, 148-154(2007) https://doi.org/10.1007/BF02875784
  87. J. Lin, C. Winkelmann, S. D. Worley, J. Kim, C-I. Wei, U. Cho, R. M. Broughton, J. I. Santiago and J. F. Williams, Biocidal polyester, J. Appl. Polym. Sci., 85(1), 177-182(2002) https://doi.org/10.1002/app.10588
  88. Y. Sun and G. Sun, Novel Regenerable Nhalamine Polymeric Biocides. III. Grafting Hydantoin-Containing Monomers onto Synthetic Fabrics, J. Appl. Polym. Sci., 81(6), 1517-1525(2001) https://doi.org/10.1002/app.1580
  89. J. Lin, C. Winkelman, S. D. Worley, R. M. Broughton and J. F. Williams, Antimicrobial Treatment of Nylon, J. Appl. Polym. Sci., 81(4), 943-947(2001) https://doi.org/10.1002/app.1515
  90. J. Lee, R. M. Broughton, J. Liang, S. D. Worley and T. S. Huang, Antimicrobial Acrylic Fiber, Research Journal of Textile and Apparel, 10, 61-66(2006) https://doi.org/10.1108/RJTA-10-04-2007-B007
  91. L. Wang, J. Xie, L. Gu and G. Sun, Preparation of Antimicrobial Polyacrylonitrile Fibers: Blending with Polyacrylonitrile-co-3-Allyl-5,5-Dimethylhydantoin, Polymer Bulletin, 56(2-3), 247-256(2006) https://doi.org/10.1007/s00289-005-0468-0
  92. Y. Sun and G. Sun, Novel Refreshable N-Halamine Polymeric Biocides: N-Chlorination of Aromatic Polyamides, Ind. Eng. Chem. Res., 43(17), 5015-5020(2004) https://doi.org/10.1021/ie030846m
  93. L. W. Blakely, M. A. Howe, D. F. Pinholster, C. E. Terry and R. H. McIntosh, U. S. Pat. 5,024,840(1991)
  94. D. E. Triestram and R. H. McIntosh, U. S. Pat. 5,474,739(1995)
  95. A. J. Isquith, E. A. Abbott and P. A. Walters, Surface Bonded Antimicrobial Activity of Organosilicon Quaternary Ammonium Chloride, Applied Microbiology, 25(2), 253-256(1973)
  96. E. A. Abbott and A. J. Isquith, U. S. Pat. 3,860,709(1975)
  97. E. A. Abbott and A. J. Isquith and P. A. Walters, U. S. Pat.3,865,728(1975)
  98. J. E. Elfersy, J. Berkner and T. C. Moses, U. S. Pat.5,954,869(1999)
  99. J. E. Elfersy, J. Berkner and T. C. Moses, U. S. Pat.6,113,815(2000)
  100. J. E. Elfersy, J. Berkner and T. C. Moses, U. S. Pat.6,120,587(2000)
  101. W. Morrison, U. S. Pat.3,959,556(1976)
  102. Helathshield Press Release, PR Newswire, June 21, 2000
  103. Healthshield Press Release, PR Newswire, April 25, 2000
  104. J. D. Payne, U. S. Pat.5,700.742(1997)
  105. D. M. Fawkes, U. S. Pat.4,655,756(1987)
  106. A. L. Brown, "Biodegradable Composite Wound Dressing" M. S. Thesis, N. C. State University College of Textiles, 1999
  107. AATCC Test Method 147: Antibacterial Assessment of Textile Materials: Parallel Streak Method
  108. AATCC Test Method 100: Assessment of Antibacterial Finishes on Textile Materials