Two New Flavonol Glycosides from the Aerial Parts of Lotus lalambensis Growing in Saudi Arabia

  • El-Youssef, Hanan M. (Department of Pharmacognosy, College of Pharmacy, King Saud University) ;
  • Murphy, Brian T. (Department of Chemistry, Virginia Polytechnic Institute and State University) ;
  • Amer, Masouda E. (Department of Pharmacognosy, College of Pharmacy, King Saud University) ;
  • Al-Rehaily, Adnan J. (Department of Pharmacognosy, College of Pharmacy, King Saud University) ;
  • Abdel-Kader, Maged S. (Department of Pharmacognosy, College of Pharmacy, King Saud University) ;
  • Kingston, David G.I. (Department of Pharmacognosy, College of Pharmacy, King Saud University)
  • Published : 2008.06.30

Abstract

Phytochemical study of the aerial parts of Lotus lalambensis Schweinf resulted in the isolation and identification of two new flavonol glycosides; kaempferol $3-O-(5"-acetyl)-apioside-7-O-{\alpha}-L-rhamnopyranoside$ (1) and kaempferol $3-O-{\alpha}-[{\beta}-D-xylosyl-(1""{\rightarrow} 2")-L-rhamnopyranoside]-7-O-{\alpha}-L-rhamnopyranoside$ (2). Structures were determined utilizing different physical, chemical, spectroscopic data including 2D-NMR experiments and HRFABMS.

Keywords

References

  1. Abdel-Ghani, A.E., Hafez, S.S., Abdel Aziz, E.M., and El-Shazly, A.M., Phytochemical and biological studies of Lotus corniculatus var. tenuifolius L. growing in Egypt. Alex. J. Pharm. Sci. 15, 103-108 (2001)
  2. Abdel-Kader, M.S., Bahler, B.D., Malone, S., Werkhoven, M.C.M., Wisse, J.H., Neddermann, K.M., Bursuker, I., and Kingston, D.G.I., Bioactive Saponins from Swartzia schomburgkii from the Suriname Rainforest. J. Nat. Prod. 63, 1461-1464 (2000)Alex. J. Pharm. Sci. https://doi.org/10.1021/np0000926
  3. Abdel-Kader, M.S., Basoudan, O.A., Alqasoumi, S.I., and Abou-Shoer, M.I., Phytochemical study of Lotus ornithopodioloides L. Nat. Prod. Sci. 13, 317-321 (2007)
  4. Agrawal, P.K., $13^C-NMR$13C-NMR of flavonoids. Elsevier, Amsterdam, 1989
  5. Chaudhary, S.A., Flora of the kingdom of Saudi Arabia. Ministry of Agriculture and Water, National Agriculture and Water Research Center, Riyadh, KSA, Vol II (part II), 2001, pp. 92
  6. El Mousallami, A.M.D, Afifi, M.S., and Hussein, S.A.M., Acetylated flavanol diglucosides from Lotus polyphyllos. Phytochemistry 60, 807-811 (2002) https://doi.org/10.1016/S0031-9422(02)00177-2
  7. El-Youssef, H.M., Murphy, B., Amer, M.E., Abdel-Kader, M.S., and Kingston, D.G.I., Phytochemical and biological study of the aerial parts of Lotus lalambensis growing in Saudi Arabia. Saudi Pharmaceutical Journal 19, 122-134 (2008)
  8. Evans, W.C., Trease and Evans' Pharmacognosy. $15^th$ ed. W. B. Saunders Company Ltd. Edinburhg, London, New York, Philadelphia, St Louis, Sydney, Toronto, 2002
  9. Harborne, J.B., Mabry, T.J., and Mabry, H., The flavonoids. Academic press, New York San Francisco, 1975
  10. Imperato, F., Kaempferol 3-O-(5"-Feruloylapioside) from Pteridium aquilinum Phytochemistry 43, 1421-1423 (1996) https://doi.org/10.1016/S0031-9422(96)00428-1
  11. Mahasneh, A.M., Screening of some indogenous Qatari medicinal plants for antimicrobial activity, Phytotherapy Research 16, 751-753 (2002) https://doi.org/10.1002/ptr.1037
  12. Migahid, A.M., Flora of Saudi Arabia. $2^nd$ ed., Riyadh University Publication, Riyadh, Saudi Arabia, 1978, pp. 337