Journal of Acupuncture Research

Korean Acupuncture & Moxibustion Medicine Society (대한침구의학회)
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Antioxidative Effects of Electro-acupuncture at $KI_6$ on Rats Treated with AAPH

조해(照海) 전침의 항산화 효과에 대한 실험적 연구

  • Kim, Yeon-Mi (Dept. of Acupuncture & Moxibustion, College of Oriental Medical, Daejeon University) ;
  • Lee, Byung-Ryul (Dept. of Acupuncture & Moxibustion, College of Oriental Medical, Daejeon University) ;
  • Hong, Kwon-Eui (Dept. of Acupuncture & Moxibustion, College of Oriental Medical, Daejeon University)
  • 김연미 (대전대학교 한의과대학 침구학교실) ;
  • 이병렬 (대전대학교 한의과대학 침구학교실) ;
  • 홍권의 (대전대학교 한의과대학 침구학교실)
  • Published : 2008.02.20
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Abstract

Objectives : This study investigated the antioxidant effect of electro-acupuncture at $KI_6$ on rats treated with 2,2'-azobis(2-amidinopropane) dihydrochloride(AAPH). Methods : After electro-acupuncture at $KI_6$ on 48 rats that were given AAPH(50mg/kg) every day, the author observed several changes in weight, liver index, albumin, total bilirubin, LDL-cholesterol, LDH, glucose, GOT, GPT, SOD and catalase activity, and glutathione, NO, and MDA concentrations. Results : 1. In the $KI_6-EA$ group, the albumin level increased and LDL-cholesterol decreased compared with the control and holder groups. 2. In the $KI_6-EA$ group, SOD activity increased compared with the holder group, glutathione concentration increased compared with the control and holder groups, and catalase activity increased compared with the control group. 3. In the $KI_6-EA$ group, NO concentration decreased compared with the control and holder groups. Conclusions : This case shows that electro-acupuncture at $KI_6$ plays a significant antioxidant role by elevating defenses against cell toxicity caused by oxidative stress and suppressing oxidative injury.

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