대한한의학방제학회지 (Herbal Formula Science)
- 제16권1호
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- Pages.79-94
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- 2008
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- 1229-1218(pISSN)
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- 2288-5641(eISSN)
지패산(芷貝散)의 항염증(抗炎症) 효능(效能)에 대한 연구(硏究)
Anti-Inflammatory Effects of Ji-Pae-San Water Extract
- Lee, Sang-Hyun (Hong ik Oriental Clinic) ;
- Park, Chan-Ki (Hyung sang Oriental Clinic)
- 발행 : 2008.06.30
초록
Although inflammatory mediators such as nitric oxide(NO) and pro-inflammatory cytokines are involved in host defense mechanism, these overproduction contributes to the pathogenesis of several diseases such as otitis media, hearing loss, periodontitis, bacterial sepsis, rheumatoid arthritis, chronic inflammation and autoimmune diseases. We investigate the anti-inflammatory effects of water extract from Ji-Pae-San(JPSWE) fomulated with Angelica dahurica plus Fritillaria Verticillata, Angelica dahurica(ADWE), and Fritillaria Verticillata(FUVE) in vitro and in vivo. Each extract inhibited the production of inflammatory mediators(NO,