Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Quantification of Experimentally Induced-Pleural Effusion in Beagle Dogs: Radiography versus CT and Ultrasonography

비글견에서 실험적으로 유발한 흉수의 정량 평가: 방사선, 컴퓨터단층촬영 및 초음파 검사 비교

  • Lee, Ki-Ja (College of Veterinary Medicine, Research Institute of Veterinary Medicine Chungnam National University) ;
  • O, I-Se (College of Veterinary Medicine, Research Institute of Veterinary Medicine Chungnam National University) ;
  • Jeong, Seong-Mok (College of Veterinary Medicine, Research Institute of Veterinary Medicine Chungnam National University) ;
  • Lee, Hee-Chun (College of Veterinary Medicine, Gyeongsang National University) ;
  • Park, Seong-Jun (College of Veterinary Medicine, Research Institute of Veterinary Medicine Chungnam National University) ;
  • Lee, Young-Won (College of Veterinary Medicine, Research Institute of Veterinary Medicine Chungnam National University) ;
  • Choi, Ho-Jung (College of Veterinary Medicine, Research Institute of Veterinary Medicine Chungnam National University)
  • 이기자 (충남대학교 수의과대학.동물의과학연구소) ;
  • 오이세 (충남대학교 수의과대학.동물의과학연구소) ;
  • 정성목 (충남대학교 수의과대학.동물의과학연구소) ;
  • 이희천 (경상대학교 수의과대학) ;
  • 박성준 (충남대학교 수의과대학.동물의과학연구소) ;
  • 이영원 (충남대학교 수의과대학.동물의과학연구소) ;
  • 최호정 (충남대학교 수의과대학.동물의과학연구소)
  • Published : 2008.04.30
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Abstract

This study was performed to quantify the pleural effusion in radiography, ultrasonography and computed tomography(CT) and to evaluate and compare the usefulness of these methods. Normal saline of 10 ml/kg was infused into the pleural space until a final loading volume of 60 ml/kg body weight was reached in six Beagle dogs. The radiographic examination was performed for the detection and quantification of pleural effusion. On the ultrasonographic study, the maximum perpendicular distance was measured between the surface of the lung and the thoracic wall to evaluate pleural effusion. On the CT image, pleural effusion was evaluated as the perpendicular distance to the thoracic surface in the maximum pleural effusion volume on any transverse images with soft tissue window. Statistical analysis was performed using linear regression test. The volume of pleural effusion and measurements of radiography and ultrasonography had no statistical relationship. However, a significant correlation was identified between the volume of pleural effusion and the depth at right ($r^2=0.715$), left ($r^2=0.745$), and mean right and left depth ($r^2=0.844$) on the CT images. All of the thoracic radiographs, ultrasonography, and CT are useful in recognition of pleural effusion. In quantification of pleural effusion, the CT measurement method is superior to radiographic and ultrasonographic measurements.

흉수량은 흉수천자의 실시 여부 및 진단과 치료에 이용되는 방법의 결정에 영향을 미치므로 흉수량 측정은 중요하다. 본 실험의 목적은 흉수를 정량화하기 위해 흉부 방사선 및 초음파와 컴퓨터단층촬영을 시행하여 그 결과를 비교하고 정확도를 측정하는데 있다. 임상적으로 건강한 6 마리의 비글견을 이용하여 생리식염수를 최종 용량이 60 ml/kg 될 때까지 체중당 10ml씩 흉강에 주입하면서 흉부 방사선 검사, 초음파 검사, CT 검사를 차례로 실시하였다. 흉부 방사선 사진에서 흉수의 유무 평가 및 흉수 정량화를 실시하였으며 초음파 영상에서 흉수량은 폐의 표면과 흉강벽 사이의 최대 수직 거리를 측정하여 평가하였다. CT 영상에서 흉수량은 soft tissue window에서 평가하였으며 최대 흉수량을 나타내는 영상에서 최소 수직거리를 측정하였다. 흉수량과 흉부 방사선 사진 및 초음파 영상에서의 측정치와 통계학적으로 유의적인 결과를 얻지 못했다. 그러나 CT 검사에서의 측정값과 흉수량과의 유의적인 관계를 나타내었다. 특히 흉수의 정량화에서 좌우측 측정치의 평균값이 좌우측 각각의 값보다 더 높은 정확도를 나타내었다. 흉수를 확인하기 위해서는 흉부 방사선 검사 초음파 검사 및 CT 검사가 모두 가능하나 흉수를 정량화하기 위해서는 흉부 방사선 및 초음파 검사보다 CT 검사가 유용함을 확인하였다.

Keywords

References

  1. Arenas-Jimenez J, Alonso-Charterina S, Sanchez-Paya J et al. Evaluation of CT findings for diagnosis of pleural effusions. Eur Radiol 2000; 10: 681-690 https://doi.org/10.1007/s003300050984
  2. Balik M, Plasil P, Waldauf P et al. Ultrasound estimation of volume of pleural fluid in mechanically ventilated patients. Intensive Care Med 2006; 32: 318-321 https://doi.org/10.1007/s00134-005-0024-2
  3. Brinkman EL, Biller D, Armbrust L. The clinical usefulness of the ventrodorsal versus dorsoventral thoracic radiograph in dogs. J Am Anim Hosp Assoc 2006; 42: 440-449 https://doi.org/10.5326/0420440
  4. Davis SD, Henschke CI, Yankelevitz DF, Cahill PT, Yi Y. MR imaging of pleural effusions. J Comput Assist Tomogr 1990; 14: 192-198 https://doi.org/10.1097/00004728-199003000-00006
  5. Dechman G, Mishima M, Bates JH. Assessment of acute pleural effusion in dogs by computed tomography. J Appl Physiol 1994; 76: 1993-1998 https://doi.org/10.1152/jappl.1994.76.5.1993
  6. Eibenberger KL, Dock WI, Ammann ME et al. Quantification of pleural effusions: sonography versus radiography. Radiology 1994; 191: 681-684 https://doi.org/10.1148/radiology.191.3.8184046
  7. Emamian SA, Kaasbol MA, Olsen JF, Pedersen JF. Accuracy of the diagnosis of pleural effusion on supine chest X-ray. Eur Radiol 1997; 7: 57-60 https://doi.org/10.1007/s003300050109
  8. Evans AL, Gleeson FV. Radiology in pleural disease: state of the art. Respirology 2004; 9: 300-312 https://doi.org/10.1111/j.1440-1843.2004.00599.x
  9. Frola C, Cantoni S, Turtulici I et al. Transudative vs exudative pleural effusions: differentiation using Gd-DTPAenhanced MRI. Eur Radiol 1997; 7: 860-864 https://doi.org/10.1007/s003300050219
  10. Kocijancic I, Vidmar K, Ivanovi-Herceg Z. Chest sonography versus lateral decubitus radiography in the diagnosis of small pleural effusions. J Clin Ultrasound 2003; 31: 69-74 https://doi.org/10.1002/jcu.10141
  11. Light RW. Pleural effusion. In: Bouros D. Pleural disease, 3rd ed. Williams and Willkins, Baltimore, 1995: 36-74
  12. Mergo PJ, Helmberger T, Didovic J et al. New formula for quantification of pleural effusions from computed tomography. J Thorac Imaging 1999; 14: 122-125 https://doi.org/10.1097/00005382-199904000-00011
  13. Myer CW. Radiography review: the vascular and bronchial patterns of pulmonary disease. Vet Radiol Ultrasound 1980; 21: 156-160 https://doi.org/10.1111/j.1740-8261.1980.tb01675.x
  14. Nandalur KR, Hardie AH, Bollampally SR, Parmar JP, Hagspiel KD. Accuracy of computed tomography attenuation values in the characterization of pleural fluid: an ROC study. Acad Radiol 2005; 12: 987-991 https://doi.org/10.1016/j.acra.2005.05.002
  15. Nelson OL. Pleural effusion. In: Ettinger SJ, Feldman EC, editors. Textbook of veterinary internal medicine, 6th ed. Elsevier sounders, Philadelphia, 2005: 204-207
  16. Porcel JM, Light RW. Diagnostic approach to pleural effusion in adults. Am Fam Physician 2006; 73: 1211-1220
  17. Prather AB, Berry CR, Thrall DE. Use of radiography in combination with computed tomography for the assessment of noncardiac thoracic disease in the dog and cat. Vet Radiol Ultrasound 2005; 46: 114-121 https://doi.org/10.1111/j.1740-8261.2005.00023.x
  18. Raasch BN, Carsky EW, Lane EJ, O'Callaghan JP, Heitzman ER. Pleural effusion: explanation of some typical appearances. Am J Roentgenol 1982; 139: 899-904 https://doi.org/10.2214/ajr.139.5.899
  19. Ruskin JA, Gurney JW, Thorsen MK, Goodman LR. Detection of pleural effusions on supine chest radiographs. Am J Roentgenol 1987; 148: 681-683 https://doi.org/10.2214/ajr.148.4.681
  20. Saunders NA, Sleeper M. Pleural transudates and modified transudates. In: King LG. Textbook of respiratory disease in dogs and cats, 1st ed. Saunders, Philadelphia, 2004: 587-597
  21. Warakaulle DR, Traill ZC. Imaging of pleural disease. Imaging 2004; 16: 10-21 https://doi.org/10.1259/imaging/32826956
  22. Woodring JH. Recognition of pleural effusion on supine radiographs: how much fluid is required? Am J Roentgenol 1984; 142: 59-64 https://doi.org/10.2214/ajr.142.1.59