Environmental Analysis Health and Toxicology

The Korean Society of Environmental Health and Toxicology (환경독성보건학회)
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Research of Detection Method for Cytotoxic Effects of Environmental Pollutants Using Atomic Force Microscopy (AFM) in HeLa Cells

원자현미경(AFM)을 이용한 환경오염물질에 노출된 HeLa 세포의 표면변화 연구

  • Lee, Si-Won (Faculty of Environmental Engineering, College of Urban Science, University of Seoul) ;
  • Lee, Soo-Il (Department of Mechnical and Information Engineering, College of Engineering, University of Seoul) ;
  • Choi, Jin-Hee (Faculty of Environmental Engineering, College of Urban Science, University of Seoul)
  • 이시원 (서울시립대학교 도시과학대학 환경공학과) ;
  • 이수일 (서울시립대학교 공과대학 기계정보공학과) ;
  • 최진희 (서울시립대학교 도시과학대학 환경공학과)
  • Published : 2008.03.31
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Abstract

The toxicity of environmental pollutants was measured between a image of the surface topography in HeLa cells using atomic force microscopy for the possibility of toxic effect measurement and environmental monitoring. A image of the surface topography by AFM were estimated as toxic endpoints. The surface topography by AFM was observed a change of the cell surface in the environmental pollutants, but the standard of the measurement requires for the dose-effect degree. The overall results indicate that the possibility of measurement using AFM were confirmed a dose-effect degree related toxic effects, but it requres correlation between more various biomarker and AFM's measurements if the possibility of the toxic effect measurement was established.

Keywords

References

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