Maxillofacial Plastic and Reconstructive Surgery

  • 제30권4호
  • /
  • Pages.395-398
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  • 2008
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  • 2288-8101(pISSN)
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  • 2288-8586(eISSN)
대한악안면성형재건외과학회 (Korean Association of Maxillofacial Plastic and Reconstructive Surgeons)
권호 표지

Bisphosphonate(Zoledronic acid)와 연관된 하악골의 골수염-증례보고

BISPHOSPHONATE(ZOLEDRONIC ACID) RELATED OSTEOMYELITIS ON MANDIBLE-A CASE REPORT

  • 이수연 (경북대학교 치과대학 구강악안면외과학교실) ;
  • 최소영 (경북대학교 치과대학 구강악안면외과학교실) ;
  • 김진욱 (경북대학교 치과대학 구강악안면외과학교실) ;
  • 권대근 (경북대학교 치과대학 구강악안면외과학교실) ;
  • 장현중 (경북대학교 치과대학 구강악안면외과학교실) ;
  • 김진수 (경북대학교 치과대학 구강악안면외과학교실) ;
  • 이상한 (경북대학교 치과대학 구강악안면외과학교실)
  • Lee, Su-Youn (Dept. of Oral & Maxillofacial Surgery, School of Dentistry, Kyungpook National University) ;
  • Choi, So-Young (Dept. of Oral & Maxillofacial Surgery, School of Dentistry, Kyungpook National University) ;
  • Kim, Jin-Wook (Dept. of Oral & Maxillofacial Surgery, School of Dentistry, Kyungpook National University) ;
  • Kwon, Tae-Geon (Dept. of Oral & Maxillofacial Surgery, School of Dentistry, Kyungpook National University) ;
  • Jang, Hyung-Jung (Dept. of Oral & Maxillofacial Surgery, School of Dentistry, Kyungpook National University) ;
  • Kim, Chin-Soo (Dept. of Oral & Maxillofacial Surgery, School of Dentistry, Kyungpook National University) ;
  • Lee, Sang-Han (Dept. of Oral & Maxillofacial Surgery, School of Dentistry, Kyungpook National University)
  • 발행 : 2008.07.31
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초록

Bisphosphonate are a class of drugs with a chemical structure which inhibit bone resorption, actually used for metastatic bone disease, osteoporosis, Paget's disease and multiple myeloma. Significant complication associated with their use is reported recently : mandibular and maxillary osteomyelitis or osteonecrosis. So we here report our case about the patient who was diagnosed of prostate cancer in 2004 April and treated with bisphosphonate(Zoledronic acid-$Zometa^{(R)}$, Novartis Co.) intravenously every 3 to 4weeks at a dose of 4mg to prevent bone metastasis, and also, the patient who came to the hospital due to the bony exposure of mandible and pain in 2006 November and was diagnosed osteomyelitis of mandible as a result of biopsy, bone scan, PET CT examination.

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참고문헌

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