동의생리병리학회지 (Journal of Physiology & Pathology in Korean Medicine)

  • 제22권1호
  • /
  • Pages.234-245
  • /
  • 2008
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  • 1738-7698(pISSN)
  • /
  • 2288-2529(eISSN)
대한동의생리학회·한의병리학회 ( The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine)
권호 표지

감기에 대한 연교패독산의 유효성 평가를 위한 community-based 이중맹검 위약 대조군 연구

Effectiveness of a Yeonkyopaedok-san Extract in the Treatment of The Common Cold : Results of a Community-based, Double Blind, Randomized Placebo Controlled Trial

  • 배한호 (대전대학교 한의과대학 폐계내과학교실) ;
  • 강위창 (대전대학교 경영대학 응용통계학과) ;
  • 박양춘 (대전대학교 한의과대학 폐계내과학교실)
  • Bae, Han-Ho (Division of Respiratory System, Department of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
  • Kang, Wee-Chang (Department of Applicative Statistics, College of Economics, Daejeon University) ;
  • Park, Yang-Chun (Division of Respiratory System, Department of Internal Medicine, College of Oriental Medicine, Daejeon University)
  • 발행 : 2008.02.25
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초록

Yeonkyopaedok-san(YPS) extract is widely used to treat the common cold. The purpose of this study was to evaluate the efficacy of YPS on the common cold. Two hundred Patients with common colds of recent onset were randomized to the double blind, placebo-controlled study. They received 800 mg YPS extract or placebo in capsules, orally dissolved 3 times a day for 7 days. The total symptom score was assessed by the physician, using a 5-point scale on start and finish. Resolution of cold symptoms based on subjective daily symptoms. Total symptom score was significantly decreased in YPS groups in comparison to that in placebo group (p=0.027). Headache (p=0.012), loss of appetite (p=0.037), eyeball discomfort (p=0.002) were more affected. Time to resolution of cold symptoms did not show significant effect (p=0.592). Adverse effects were less in the YPS group than placebo group (2% vs 3%). In this community-based, randomized controlled trial, YPS were effective in treating cold symptoms in college students.

키워드

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