Journal of Magnetics

The Korean Magnetics Society (한국자기학회)
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Detection of Magnetic Nanoparticles and Fe-hemoglobin inside Red Blood Cells by Using a Highly Sensitive Spin Valve Device

  • Park, Sang-Hyun (School of Physics and Astronomy, Seoul National University) ;
  • Soh, Kwang-Sup (School of Physics and Astronomy, Seoul National University) ;
  • Hwang, Do-Guwn (Department of Oriental Biomedical Engineering, Sangji University) ;
  • Rhee, Jang-Roh (Department of Physics, Sookmyung Women's University) ;
  • Lee, Sang-Suk (Department of Oriental Biomedical Engineering, Sangji University)
  • Published : 2008.03.31
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Abstract

A highly sensitive, giant magnetoresistance-spin valve (GMR-SV) biosensing device with high linearity and very low hysteresis was fabricated by photolithography. The detection of magnetic nanoparticles and Fe-hemoglobin inside red blood cells using the GMR-SV biosensing device was investigated. When a sensing current of 1 mA was applied to the current electrode in the patterned active devices with an area of $2{\times}6{\mu}m^2$, the output signals were about 13.35 mV. The signal from even one drop of human blood and nanoparticles in distilled water was sufficient for their detection and analysis.

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