Korean Journal of Biological Psychiatry (생물정신의학)

The Korean Society of Biological Psychiatry (대한생물정신의학회)
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Characteristics of Heart Rate Variability Among Adults with Metabolic Syndrome

대사증후군 집단의 심박동수 변이의 특징

  • Yeo, Do Hwan (Department of Neuropsychiatry and Stress Research Institute, Seoul Paik Hospital, Inje University School of Medicine) ;
  • Kim, Jeong Il (Department of Occupational Medicine, College of Medicnie, Dong-A University) ;
  • Kang, Dong Mug (Department of Preventive and Occupational Medicine, Pusan University School of Medicine) ;
  • Kim, Jeong Yeon (Worker Health Protection Division, Occupational Safety and Health Bureau, Ministry of Labor) ;
  • Cho, Jung Hin (Department of Family Medicine, Sacred Heart Hospital, Hallym University College of Medicine) ;
  • Kim, Won (Department of Neuropsychiatry and Stress Research Institute, Seoul Paik Hospital, Inje University School of Medicine) ;
  • Lim, Seong Kyeon (Department of Neuropsychiatry and Stress Research Institute, Seoul Paik Hospital, Inje University School of Medicine) ;
  • Woo, Jong-Min (Department of Neuropsychiatry and Stress Research Institute, Seoul Paik Hospital, Inje University School of Medicine)
  • 여도환 (인제대학교 의과대학 서울백병원 신경정신과학교실 및 스트레스 연구소) ;
  • 김정일 (동아대학교 의과대학 산업의학교실) ;
  • 강동묵 (부산대학교 의학전문대학원 예방의학 및 산업의학교실) ;
  • 김정연 (노동부 산업안전보건국 근로자건강보호과) ;
  • 조정진 (한림대학교 의과대학 성심병원 가정의학과학교실) ;
  • 김원 (인제대학교 의과대학 서울백병원 신경정신과학교실 및 스트레스 연구소) ;
  • 임성견 (인제대학교 의과대학 서울백병원 신경정신과학교실 및 스트레스 연구소) ;
  • 우종민 (인제대학교 의과대학 서울백병원 신경정신과학교실 및 스트레스 연구소)
  • Published : 2008.08.31
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Abstract

Objectives : The authors tried to investigate the characteristics of Heart Rate Variability(HRV) among the subjects with metabolic syndrome for testing the possibility of clinical application of HRV in evaluating metabolic syndrome. Methods : We examined the difference of the means of HRV between 122 subjects of metabolic syndrome and 1057 healthy controls using T-test, and the change of means in HRV according to increasing risk factors of metabolic syndrome. Using multiple regression analysis, we examined the association of HRV with the risk factors of metabolic syndrome. Results : The HRV indices including SDNN(Standard Deviation of all normal NN intervals), RMSSD(the square Root of the Mean Squared Differences of successive all normal NN interval), TP(Total Power), LF(Low Freuency), and HF(High Frequency) were significantly lower in the metabolic syndrome group than in the normal control group, and the means of all HRV indices except LF/HF were decreased consistently according to increasing risk factors of metabolic syndrome. The fasting glucose, triglyceride, and waist circumference were dependent factors that contributed significantly to the change of HRV. Conclusion : These findings suggest metabolic syndrome adversely affects cardiac autonomic system and HRV could be a useful method for evaluating metabolic syndrome.

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