대한수의학회지 (Korean Journal of Veterinary Research)

  • 제48권1호
  • /
  • Pages.93-98
  • /
  • 2008
  • /
  • 2466-1384(pISSN)
  • /
  • 2466-1392(eISSN)
대한수의학회 (The Korean Society of Veterinary Science)
권호 표지

Intracranial anaplastic oligodendroglioma concurrent with hydrocephalus and syringomyelia in a Boston terrier dog

  • Park, Chul (School of Veterinary Medicine, University of California Davis) ;
  • Kang, Byeong-Teck (College of Veterinary Medicine, Konkuk University) ;
  • Yoo, Jong-Hyun (College of Veterinary Medicine, Konkuk University) ;
  • Kim, Ha-Jung (College of Veterinary Medicine, Konkuk University) ;
  • Jung, Dong-In (College of Veterinary Medicine, Konkuk University) ;
  • Lim, Chae-Young (College of Veterinary Medicine, Konkuk University) ;
  • Kim, Jae-Hoon (College of Veterinary Medicine, Jeju National University) ;
  • Woo, Eung-Je (College of Electronics and Information, Kyunghee University) ;
  • Kang, Sang-Chul (Preclinical Research Center, Chemon Inc.) ;
  • Park, Hee-Myung (College of Veterinary Medicine, Konkuk University)
  • 심사 : 2008.02.04
  • 발행 : 2008.03.30
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

A 6-year-old female Boston terrier dog was presented with seizure episode, forelimb paraparesis, excessive panting, and ataxia. On physical and neurological examination, episcleral vessel engorgement, delayed postural reaction, delayed pupillary light reflex (both direct and consensual), and crossed forelimb were noted. Serum biochemical profiles were not remarkable other than mildly elevated hepatic enzymes. On cerebrospinal fluid analysis, elevated protein concentration was observed. In magnetic resonance imaging scans, the left frontal brain lesion with ring enhancement strongly suggested the presence of intracranial tumor. Concurrently, secondary hydrocephalus and syringomyelia were also observed. The dog was euthanized at 4 months after initial presentation because of aggravated neurological signs. This case was definitely diagnosed as an intracranial anaplastic oligodendroglioma based on postmortem histopathologic examination.

키워드

참고문헌

  1. Bagley RS, Gavin PR, Moore MP, Silver GM, Harrington ML, Connors RL. Clinical signs associated with brain tumors in dogs: 97 cases (1992- 1997). J Am Vet Med Assoc 1999, 215, 818-819
  2. da Costa RC, Parent JM, Poma R, Duque MC. Cervical syringohydromyelia secondary to a brainstem tumor in a dog. J Am Vet Med Assoc 2004, 225, 1061-1064 https://doi.org/10.2460/javma.2004.225.1061
  3. Daumas-Duport C, Varlet P, Tucker ML, Beuvon F, Cervera P, Chodkiewicz JP. Oligodendrogliomas. Part I: Patterns of growth, histological diagnosis, clinical and imaging correlations: a study of 153 cases. J Neurooncol 1997, 34, 37-59 https://doi.org/10.1023/A:1005707203596
  4. Dewey CW. Encephalopathies. Disorders of the brain. In: Dewey CW (ed.). A Practical Guide to Canine and Feline Neurology. 1st ed. pp. 127-136, Iowa State Press, Ames, 2003
  5. Engelhard HH, Stelea A, Cochran EJ. Oligodendroglioma: pathology and molecular biology. Surg Neurol 2002, 58, 111-117 https://doi.org/10.1016/S0090-3019(02)00751-6
  6. Hayes KC, Schiefer B. Primary tumors in the CNS of carnivores. Pathol Vet 1969, 6, 94-116 https://doi.org/10.1177/030098586900600202
  7. Itoh T, Nishimura R, Matsunaga S, Kadosawa T, Mochizuki M, Sasaki N. Syringomyelia and hydrocephalus in a dog. J Am Vet Med Assoc 1996, 209, 934-936
  8. Johnson GC. Genesis and pathology of tumors of the nervous system. Semin Vet Med Surg (Small Anim) 1990, 5, 210-222
  9. Jung DI, Park C, Kang BT, Kim JW, Kim HJ, Lim CY, Jeong SW, Park HM. Acquired cervical syringomyelia secondary to a brainstem meningioma in a maltese dog. J Vet Med Sci 2006, 68, 1235-1238 https://doi.org/10.1292/jvms.68.1235
  10. Kirberger RM, Jacobson LS, Davies JV, Engela J. Hydromyelia in the dog. Vet Radiol Ultrasound 1997, 38, 30-38 https://doi.org/10.1111/j.1740-8261.1997.tb01599.x
  11. Klekamp J, Samii M, Tatagiba M, Sepehrnia A. Syringomyelia in association with tumours of the posterior fossa. Pathophysiological considerations, based on observations on three related cases. Acta Neurochir (Wien) 1995, 137, 38-43 https://doi.org/10.1007/BF02188778
  12. Koestner A, Bilzer T, Fatzer R, Schulman FY, Summers BA, Van Winkle TJ. Histological Classification of the Tumors of the Nervous System of Domestic Animals. WHO International Histological Classification of Tumors of Domestic Animals. 2nd series. vol. 5. pp. 26-27, Armed Forces Institute of Pathology, Washington DC, 1999
  13. Koziarski A, Zieli ski G. Syringomyelia associated with intracranial tumors. Case report and literature review. Neurol Neurochir Pol 2001, 35,139-152
  14. Kraft SL, Gavin PR, DeHaan C, Moore M, Wendling LR, Leathers CW. Retrospective review of 50 canine intracranial tumors evaluated by magnetic resonance imaging. J Vet Intern Med 1997, 11, 218-225 https://doi.org/10.1111/j.1939-1676.1997.tb00094.x
  15. LeCouteur RA. Current concepts in the diagnosis and treatment of brain tumours in dogs and cats. J Small Anim Pract 1999, 40, 411-416 https://doi.org/10.1111/j.1748-5827.1999.tb03113.x
  16. MacKillop E, Schatzberg SJ, De Lahunta A. Intracranial epidermoid cyst and syringohydromyelia in a dog. Vet Radiol Ultrasound 2006, 47, 339-344 https://doi.org/10.1111/j.1740-8261.2006.00150.x
  17. Shores A. Magnetic resonance imaging. Vet Clin North Am Small Anim Pract 1993, 23, 437-459 https://doi.org/10.1016/S0195-5616(93)50036-0
  18. Snyder JM, Shofer FS, Van Winkle TJ, Massicotte C. Canine intracranial primary neoplasia: 173 cases (1986-2003). J Vet Intern Med 2006, 20, 669-675 https://doi.org/10.1892/0891-6640(2006)20[669:CIPNC]2.0.CO;2
  19. Taga A, Taura Y, Nakaichi M, Wada N, Hasegawa T. Magnetic resonance imaging of syringomyelia in five dogs. J Small Anim Pract 2000, 41, 362-365 https://doi.org/10.1111/j.1748-5827.2000.tb03221.x
  20. Targett MP, McInnes E, Dennis R. Magnetic resonance imaging of a medullary dermoid cyst with secondary hydrocephalus in a dog. Vet Radiol Ultrasound 1999, 40, 23-26 https://doi.org/10.1111/j.1740-8261.1999.tb01834.x
  21. Taylor RF, Bucci TJ. Oligodendroglioma in a dog. J Small Anim Pract 1972, 13, 41-46 https://doi.org/10.1111/j.1748-5827.1972.tb06796.x
  22. Triolo AJ, Howard MO, Miles KG. Oligodendroglioma in a 15-month-old dog. J Am Vet Med Assoc 1994, 205, 986-988
  23. van den Bent MJ. Diagnosis and management of oligodendroglioma. Semin Oncol 2004, 31, 645-652 https://doi.org/10.1053/j.seminoncol.2004.07.006
  24. Wilson RB, Beckman SL. Mucinous oligodendroglioma of the spinal cord in a dog. J Am Anim Hosp Assoc 1995, 31, 26-28 https://doi.org/10.5326/15473317-31-1-26
  25. Zabka TS, Lavely JA, Higgins RJ. Primary intraaxial leiomyosarcoma with obstructive hydrocephalus in a young dog. J Comp Pathol 2004, 131, 334-337 https://doi.org/10.1016/j.jcpa.2004.04.006