하구순부에 발생한 미세낭포성 피부부속기 암의 치험례

Microcystic Adnexal Carcinoma of the Lower lip: A Case Report

  • 이재수 (연세대학교 의과대학 인체조직복원연구소.성형외과학교실) ;
  • 나동균 (연세대학교 의과대학 인체조직복원연구소.성형외과학교실) ;
  • 김상겸 (연세대학교 의과대학 인체조직복원연구소.병리학교실) ;
  • 탁관철 (연세대학교 의과대학 인체조직복원연구소.성형외과학교실)
  • Lee, Chae Su (Institute for Human Tissue Restoration, Department of Plastic & Reconstructive Surgery, Yonsei University College of Medicine) ;
  • Rah, Dong Kyun (Institute for Human Tissue Restoration, Department of Plastic & Reconstructive Surgery, Yonsei University College of Medicine) ;
  • Kim, Sang Kyum (Institute for Human Tissue Restoration, Department of Pathology, Yonsei University College of Medicine) ;
  • Tark, Kwan Chul (Institute for Human Tissue Restoration, Department of Plastic & Reconstructive Surgery, Yonsei University College of Medicine)
  • 투고 : 2008.01.23
  • 발행 : 2008.05.10

초록

Purpose: Microcystic adnexal carcinoma is a rare malignant appendage tumor, first described by Goldstein et al in 1982. Here, we present our experience in treatment of a case on the lower lip. Methods: A 52-year-old female with an asymptomatic nodule on the chin, previously misdiagnosed as trichoadenoma by needle aspiration biopsy, was treated by wide excision combined with multiple circumferential frozen biopsies. Results: Pathological examination revealed typical features of microcystic adnexal carcinoma, such as basaloid and squamous cells forming nests and cord-like patterns, horn cysts, and minimal cytologic atypia. The patient has been followed up for 6 months. No sign of recurrence is noted to date. Conclusion: Differentiation from other benign adnexal neoplasms is important for its appropriate treatment. Differentiation can be difficult histologically because it is difficult to acquire an adequate biopsy due to its invasiveness, and clinically due to its asymptomatic and slow growing features. Complete excision is the key treatment, but it may not always be the best solution considering the huge defect that may result and the low incidence of metastasis & deaths owing to the tumor. We add this case to the approximately 300 cases reported worldwide with a review of literature.

키워드

참고문헌

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