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A case of subcutaneous paragonimiasis presented with pleural effusion

흉수를 동반한 피하조직 이소기생 폐흡충증

  • Kim, Soo Young (Department of Pediatrics, Chonnam National University Medical School) ;
  • Park, Sun Ju (Department of Pediatrics, Chonnam National University Medical School) ;
  • Bae, Si Young (Department of Pediatrics, Chonnam National University Medical School) ;
  • Cho, Young Kuk (Department of Pediatrics, Chonnam National University Medical School) ;
  • Kim, Chan Jong (Department of Pediatrics, Chonnam National University Medical School) ;
  • Woo, Young Jong (Department of Pediatrics, Chonnam National University Medical School) ;
  • Choi, Young Youn (Department of Pediatrics, Chonnam National University Medical School) ;
  • Ma, Jae Sook (Department of Pediatrics, Chonnam National University Medical School) ;
  • Hwang, Tai Ju (Department of Pediatrics, Chonnam National University Medical School)
  • 김수영 (전남대학교 의과대학 소아과학교실) ;
  • 박선주 (전남대학교 의과대학 소아과학교실) ;
  • 배시영 (전남대학교 의과대학 소아과학교실) ;
  • 조영국 (전남대학교 의과대학 소아과학교실) ;
  • 김찬동 (전남대학교 의과대학 소아과학교실) ;
  • 우영종 (전남대학교 의과대학 소아과학교실) ;
  • 최영륜 (전남대학교 의과대학 소아과학교실) ;
  • 마재숙 (전남대학교 의과대학 소아과학교실) ;
  • 황태주 (전남대학교 의과대학 소아과학교실)
  • Received : 2008.02.02
  • Accepted : 2008.05.17
  • Published : 2008.07.15

Abstract

Paragonimiasis is a parasitic infection that occurs following the ingestion of infectious Paragonimus metacercariae from crabs or crayfish. Pulmonary paragonimiasis is the most common clinical manifestation of this infection, but several ectopic paragonimiasis cases have also been reported. Among them, cases of subcutaneous paragonimiasis are rare, especially in children. We report a case of subcutaneous paragonimiasis of the right abdominal wall with pleural effusion with hepatic involvement and without abnormal pulmonary infiltration in a boy aged 2 years and 5 months. He had eaten soybean sauce-soaked freshwater crabs (kejang) 6 months prior to complaining of right abdominal wall distension. On evaluation, right pleural effusion without abnormal pulmonary infiltration was detected, as well as blood eosinophilia, an elevated serum IgE level, pleural fluid eosinophilia and a positive enzyme-linked immunosorbent assay that detected P. westermani antibody in the serum. Thoracentesis, praziquantel administration, and excision of subcutaneous lesions were performed. After treatment, the eosinophil count and serum IgE level were decreased, and the subcutaneous lesions did not recur. The frequency of paragonimiasis has decreased recently, but it is still prevalent in Korea. Paragonimiasis should be suspected if pleural fluid eosinophilia is associated with blood hypereosinophilia and a high level of serum IgE; however clinicians should obtain a thorough history of travel and food habits.

폐흡충증은 갑각류나 생가재 내의 Paragonimus의 유충의 섭취로 발생하는 기생충 감염이다. 폐 폐흡충증이 가장 흔한 임상 양상이지만 몇몇 이소 폐흡충증이 보고되고 있다. 그 가운데 피하조직의 폐흡충증은 매우 드물다. 6개월 전 게장을 먹은 과거력이 있는 2세 5개월 남아가 우측 복벽의 종류를 주소로 내원하였다. 흉부 X선과 CT 상 폐실질에 이상 없이 우측 흉수만 발견되었고 간비대를 보이고 있었다. 말초혈액 검사상 호산구 증다증을 동반한 백혈구 증가증 및 혈청 면역글로불린 E의 상승을 보였다. 이후 ELISA 상 폐흡충 항체에 양성반응을 보여 P. westermani에 의한 흉수를 동반한 피하조직의 폐흡충증으로 진단할 수 있었다. 환아는 praziquantel 복용으로 치료를 하였으나 피하조직의 폐흡충증 종류가 더 악화되어 이를 수술적으로 제거하였고 조직검사상 기생충의 감염으로 의심되는 염증반응을 관찰할 수 있었다. 이에 본 저자들은 소아에서 감염된 피하조직의 폐흡충증의 드문 증례를 보고하는 바이다.

Keywords

References

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