Opioid-induced Muscle Rigidity with a Delayed Manifestation Misunderstood as a Tension Pneumothorax -A case report-

긴장성 기흉으로 오인된 지연 발현된 아편양 제제 유발 근경축 -증례보고-

  • Kang, Bong Jin (Department of Anesthesiology and Pain Medicine, Dankook University College of Medicine) ;
  • Kim, Sung Hoon (Department of Anesthesiology and Pain Medicine, Dankook University College of Medicine)
  • 강봉진 (단국대학교 의과대학 마취통증의학교실) ;
  • 김성훈 (단국대학교 의과대학 마취통증의학교실)
  • Received : 2007.10.04
  • Accepted : 2007.12.20
  • Published : 2008.06.01

Abstract

Opioid-induced rigidity is a potentially life-threatening complication that can occur after treatment with large doses of opioids, but with early recognition it can be treated effectively with naloxone or with muscle relaxants. Regarding its onset time, there have been few case reports that have described delayed manifestations of opioid-induced rigidity. The mechanism of this complication is not well understood. In this report we describe a case of incidental overdose injection of sufentanil and subsequently review the confusing clinical features that require immediate diffenrentiation and the possible mechanim of this complication.

Keywords

References

  1. Bailey PL, Egan TD, Stanley TH: Intravenous opioid anesthetics. In: Anesthesia. 5th ed. Edited by Miller RD: Philiadelphia, Churchill Livingstone. 2000, pp 273-376
  2. Park JW: Anesthetic induction using fentanyl. Korean J Anesthesiol 1989; 22: 872-8 https://doi.org/10.4097/kjae.1989.22.6.872
  3. Benthuysen JL, Smith NT, Sanford TJ, Head N, Dec-Silver H: Physiology of alfentanil-induced rigidity. Anesthesiology 1986; 64: 440-6 https://doi.org/10.1097/00000542-198604000-00005
  4. Goldberg M, Ishak S, Garcia C, McKenna J: Postoperative rigidity following sufentanil administration. Anesthesiology 1985; 63: 199-201
  5. Christian CM 2nd, Waller JL, Moldenhauer CC: Postoperative rigidity following fentanyl anesthesia. Anesthesiology 1983; 58: 275-7 https://doi.org/10.1097/00000542-198303000-00015
  6. Leigh-Smith S, Harris T: Tension pneumothorax-time for a re-think? Emerg Med J 2005; 22: 8-16 https://doi.org/10.1136/emj.2003.010421
  7. Kitagawa N, Oda M, Totoki T: Meperidine-induced muscular rigidity during spinal anesthesia? Anesth Analg 2006; 103: 490-1 https://doi.org/10.1213/01.ANE.0000227061.74598.D9
  8. Bowdle TA, Rooke GA: Postoperative myoclonus and rigidity after anesthesia with opioids. Anesth Analg 1994; 78: 783-6
  9. Hug CC Jr, Murphy MR: Tissue redistribution of fentanyl and termination of its effects in rats. Anesthesiology 1981; 55: 369-75 https://doi.org/10.1097/00000542-198110000-00006
  10. Streisand JB, Bailey PL, Lemaire L, Ashburn MA, Tarver SD, Varvel J, et al: Fentanyl-indeced rigidity and unconsciousness in human volunteers. Incidence, duration, and plasma concentrations. Anesthesiology 1993; 78: 629-34 https://doi.org/10.1097/00000542-199304000-00003
  11. Abrams JT, Horrow JC, Bennett JA, Van Riper DF, Storella RJ: Upper airway closure: a primary source of difficult ventilation with sufentanil induction of anesthesia. Anesth Analg 1996; 83: 629-32 https://doi.org/10.1097/00000539-199609000-00034
  12. Arandia HY, Patil VU: Glottic closure following large doses of fentanyl. Anesthesiology 1987; 66: 574-5
  13. Fahnenstich H, Steffan J, Kau N, Bartmann P: Fentanyl-induced chest wall rigidity and laryngospasm in preterm and term infants. Crit Care Med 2000; 28: 836-9 https://doi.org/10.1097/00003246-200003000-00037
  14. Lalley PM: Mu-opioid receptor agonist effects on medullary respiratory neurons in the cat: evidence for involvement in certain types of ventilatory disturbances. Am J Physiol Regul Integr Comp Physiol 2003; 285: R1287-304 https://doi.org/10.1152/ajpregu.00199.2003
  15. Vankova ME, Weinger MB, Chen DY, Bronson B, Motis V, Koob GF: Role of central mu, delta-1, and kappa-1 opioid receptors in opioid-induced muscle rigidity in the rat. Anesthesiology 1996; 85: 574-83 https://doi.org/10.1097/00000542-199609000-00017
  16. Weinger MB, Smith NT, Blasco TA, Koob GF: Brain sites mediating opiate-induced muscle rigidity in the rat: methylnaloxonium mapping study. Brain Res 1991; 544: 181-90 https://doi.org/10.1016/0006-8993(91)90052-W
  17. Roy S, Fortier LP: Fentanyl-induced rigidity during emergence from general anesthesia potentiated by venlafexine. Can J Anaesth 2003; 50: 32-5 https://doi.org/10.1007/BF03020183
  18. Weinger MB, Segal IS, Maze M: Dexmedetomidine, acting through central alpha-2 adrenoceptors, prevents opiate-induced muscle rigidity in the rat. Anesthesiology 1989; 71: 242-9
  19. Sanford TJ Jr, Weinger MB, Smith NT, Benthuysen JL, Head N, Silver H, et al: Pretreatment with sedativehypnotics, but not with nondepolarizing muscle relaxants, attenuates alfentanil-induced muscle rigidity. J Clin Anesth 1994; 6: 473-80 https://doi.org/10.1016/0952-8180(94)90087-6
  20. Fu MJ, Tsen LY, Lee TY, Lui PW, Chan SH: Involvement of cerulospinal glutamatergic neurotransmission in fentanyl-induced muscular rigidity in the rat. Anesthesiology 1997; 87: 1450-9 https://doi.org/10.1097/00000542-199712000-00024