대한수의학회지 (Korean Journal of Veterinary Research)

  • 제48권3호
  • /
  • Pages.259-265
  • /
  • 2008
  • /
  • 2466-1384(pISSN)
  • /
  • 2466-1392(eISSN)
대한수의학회 (The Korean Society of Veterinary Science)
권호 표지

국내 가금유래 병원성 대장균의 extended-spectrum β-lactamase(ESBL) 특성 조사

Survey of extended-spectrum β-Lactamase (ESBL) in pathogenic Escherichia coli isolated from poultry in Korea

  • 성명숙 (경북대학교 수의과대학) ;
  • 김진현 (경북대학교 수의과대학) ;
  • 조재근 (대구시 보건환경연구원) ;
  • 설성용 (경북대학교 의학전문대학원) ;
  • 김기석 (경북대학교 수의과대학)
  • Sung, Myung-Suk (College of Veterinary Medicine, Kyungpook National University) ;
  • Kim, Jin-Hyun (College of Veterinary Medicine, Kyungpook National University) ;
  • Cho, Jae-Keun (Health & Environmental Research Institute) ;
  • Seol, Sung-Yong (Kyungpook National University School of Medicine) ;
  • Kim, Ki-Seuk (College of Veterinary Medicine, Kyungpook National University)
  • 심사 : 2008.08.28
  • 발행 : 2008.12.01
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초록

This study was conducted to investigate incidence of extended-spectrum ${\beta}$-lactamase (ESBL) producing strains and characteristics of ESBL gene in pathogenic Escherichia coli isolated from poultry during the period from April 2003 to December 2005 in Korea. Among 203 isolates, 4 isolates (3 from broilers and 1 from layer) were confirmed as ESBL producing strains by double disk synergy test, polymerase chain reaction and sequencing for ${\beta}$-lactamase genes. $bla_{CTX-M-15}$ and $bla_{CMY-2}$ were detected in these 4 isolates and were transferred to recipient by conjugation, respectively. Also, these ESBL producing strains were associated with multiple drug resistance. In conclusion, these results exhibit incidence of CTX-M and CMY-2 ${\beta}$-lactamase in pathogenic E coli from poultry in Korea, and clinically important meaning in human. And they also suggest the needs for rapid and broad surveillance to monitor ESBL genes and R plasmid transferring resistant gene in poultry.

키워드

참고문헌

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