Asian-Australasian Journal of Animal Sciences

Asian Australasian Association of Animal Production Societies (아세아태평양축산학회)
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Effect of Overfeeding on Plasma Parameters and mRNA Expression of Genes Associated with Hepatic Lipogenesis in Geese

  • Han, Chunchun (Key Lab of Animal Genetic Resources, College of Animal Science and Technology Sichuan Agricultural University) ;
  • Wang, Jiwen (Key Lab of Animal Genetic Resources, College of Animal Science and Technology Sichuan Agricultural University) ;
  • Xu, Hengyong (Key Lab of Animal Genetic Resources, College of Animal Science and Technology Sichuan Agricultural University) ;
  • Li, Liang (Key Lab of Animal Genetic Resources, College of Animal Science and Technology Sichuan Agricultural University) ;
  • Ye, Jianqiang (Key Lab of Animal Genetic Resources, College of Animal Science and Technology Sichuan Agricultural University) ;
  • Li, Jiang (Key Lab of Animal Genetic Resources, College of Animal Science and Technology Sichuan Agricultural University) ;
  • Zhuo, Weihua (Key Lab of Animal Genetic Resources, College of Animal Science and Technology Sichuan Agricultural University)
  • Received : 2007.08.22
  • Accepted : 2007.12.02
  • Published : 2008.04.01
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Abstract

The aim of our study was to research the effect of overfeeding on plasma parameters and mRNA expression of genes associated with hepatic lipogenesis in the Sichuan white goose and Landes goose. Fifty-four male Landes geese and 57 male Sichuan white geese were hatched on the same day under the same feeding conditions. After overfeeding for 14 days, (1) extrahepatic adipose tissues grew greatly in the Sichuan white geese, while more lipid accumulated in liver tissue in the Landes geese. (2) Sichuan white geese had a higher plasma concentration of triacylglycerols (TG), lipoproteins and insulin than the Landes geese. However, the Landes geese exhibited higher increase of plasma concentrations of TG, lipoproteins and insulin, with greater decrease of the diacylglycerol acyltransferase 2 (DGAT2) activity and DGAT2 mRNA level and a smller decrease of plasma glucose concentration. In addition, the mRNA level of MTP and LPL in liver was down- and up- regulated by overfeeding, respectively. (3) The correlations between the activity of LPL and the proportions of subcutaneous adipose tissue, abdominal adipose tissue, and liver weight, and the plasma concentration of VLDL were different in the two breeds. (4) The proportion of fatty liver weight was positively correlated to plasma concentrations of VLDL and TG in the overfed Sichuan white geese. Such a relationship did not exist in the Landes geese. (5) The activity of DGAT2 and its mRNA abundance in liver had significant negative correlations with the TG content in liver lipid and plasma insulin level in the Landes geese, while in the Sichuan white geese they had negative correlation (p>0.05) with TG concentration in liver lipid and had significant positive correlation with VLDL and TG concentrations in plasma.

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