DOI QR코드

DOI QR Code

Evaluating and managing hypertension in children: a survey of Korean cardiologists and nephrologists

소아 고혈압의 평가와 관리 방법; 한국 소아심장 전문의와 소아신장 전문의 설문

  • 이은희 (고려대학교 의과대학 소아과학교실) ;
  • 임형은 (고려대학교 의과대학 소아과학교실) ;
  • 장기영 (고려대학교 의과대학 소아과학교실) ;
  • 유기환 (고려대학교 의과대학 소아과학교실) ;
  • 손창성 (고려대학교 의과대학 소아과학교실) ;
  • 홍영숙 (고려대학교 의과대학 소아과학교실) ;
  • 이주원 (고려대학교 의과대학 소아과학교실)
  • Received : 2008.03.11
  • Accepted : 2008.08.05
  • Published : 2008.09.15

Abstract

Purpose : Hypertension (HTN) is no longer an exclusively adult disease; the prevalence of pediatric HTN is increasing. To understand the evaluation and treatment of childhood HTN in Korea, we investigated, via a questionnaire, how hypertensive children are currently assessed and managed by pediatric cardiologists (CA) and nephrologists (NE). Methods : We surveyed 82 pediatric CA and 77 NE, regarding how they manage hypertensive children in Korea. Results : A total 75 replies were received to our questionnaire request (response rate: 47.15%). Routine blood pressure (BP) checks were more frequently performed by NE (CA: 5.7%, NE: 25%, P=0.03), but most respondents (86%) did not check BP routinely. Mercury sphygmomanometers were the most commonly used devices and ambulatory blood pressure monitoring was not frequently used. The goal BP in treated patients was set at the 95th percentile by 61% of respondents. NE used a lower BP goal in hypertensive children with renal disease (CA: 24%, NE: 64%, P=0.004) or DM (CA: 12.5%, NE: 50%, P=0.003). Angiotensin converting enzyme (ACE) inhibitors were the most commonly used agents (mean: 59%); following ACE inhibitors, CA preferred diuretics for hypertensive children with renal disease or cardiovascular disease, and NE preferred calcium channel blockers, regardless of underlying disease. Self-monitoring was the most frequent method for BP monitoring at home. Conclusion : In Korea, BP measurement is not yet a routine examination in treating hypertension. There are some differences in management strategies vis-$\grave{a}$-vis hypertension, between pediatric cardiologists and nephrologists. For the appropriate management and prevention of secondary disease in long-term studies, standard guidelines and education are needed for pediatricians.

목 적 : 성인질환으로 여겨지던 고혈압이 소아에서도 최근 유병률이 증가 추세에 있다. 이에 한국에서 고혈압 환아의 평가 및 관리가 어떻게 이루어지고 있는지 알아보고자 하였다. 방 법 : 2006년 8월에서 10월까지 대한소아신장학회와 대한소아심장학회의 회원인 소아 전문의를 대상으로 소아 고혈압의 접근, 혈압 측정법, 혈압 조절 목표 및 약물 치료 등 에 대해서 설문을 하였다. 결 과 : 대부분의 소아 심장 전문의와 소아 신장 전문의는 아직까지 일반 소아 환자에게 일상적으로 혈압 측정을 하고 있지 않았으며 비만과 관련하여 체질량 지수 측정도 일상적으로 이루어지지 않았다. 혈압계는 주로 수은혈압계를 사용하고 있었으며 소아 신장 전문의보다 소아 심장 전문의에서 ABPM의 사용도가 높았다. 약물 치료 시 일차선택제로는 ACE 억제제가 가장 많이 이용되었으며 소아 심장 전문의 보다 소아 신장 전문의가 경우에 따라 다양한 약제를 선호하는 것으로 나타났다. 또한 혈압 조절 목표로는 나이, 성별, 키에 대한 95 백분위를 주로 사용하였으며 대부분의 응답자가 기저질환에 따라 다른 목표를 갖지 않는 것으로 나타났다. 결 론 : 한국에서는 아직까지 소아 환자 진료 시에 고혈압에 대한 선별검사를 일상적으로 하고 있지는 않았다. 사용하는 혈압계나 일차 선택제는 큰 차이를 보이지는 않았지만 소아 신장 전문의와 소아 심장 전문의 간에 고혈압 치료제 선택에 있어 차이를 보였다. 좀 더 정확한 현황을 파악하기 위해서는 개원의를 포함한 광범위의 설문이 필요할 것이며 이를 토대로 우리 실정에 맞는 소아 고혈압의 접근과 치료에 관한 지침이 세워져야 할 것이다.

Keywords

References

  1. National High Blood Pressure Education Program Working Group on Hypertension Control in Children and Adolescents. The fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents. Pediatrics 2004;114:555-76 https://doi.org/10.1542/peds.114.2.S2.555
  2. Bagga A, Jain R, Vijayakumar M, Kanitkar M, Ali U. Evaluation and management of hypertension. Indian Pediatr 2007;44:103-21
  3. Sorof JM, Lai D, Turner J, Poffenbarger T, Portman RJ. Overweight, ethnicity, and the prevalence of hypertension in school-aged children. Pediatrics 2004;113:475-82 https://doi.org/10.1542/peds.113.3.475
  4. Woroniecki RP, Flynn JT. How are hypertensive children evaluated and managed? A survey of North American pediatric nephrologists. Pediatr Nephrol 2005;20:791-7 https://doi.org/10.1007/s00467-004-1804-6
  5. National Heart, Lung, and Blood Institute, Bethesda, Maryland. Report of the second task force on blood pressure control in children-1987. Task force on blood pressure control in children. Pediatrics 1987;79:1-25
  6. National High Blood Pressure Education Program Working Group on Hypertension Control in Children and Adolescents. Update on the 1987 task force report on high blood pressure in children and adolescents: a working group report from the national high blood pressure education program. Pediatrics 1996;98:649-58
  7. Flynn JT, Daniels SR. Pharmacologic treatment of hypertension in children and adolescents. J Pediatr 2006;149:746-54 https://doi.org/10.1016/j.jpeds.2006.08.074
  8. Lande MB, Flynn JT. Treatment of hypertension in children and adolescents. Pediatr Nephrol [Epub ahead of print]
  9. Varda NM, Gregoric A. A diagnostic approach for the child with hypertension. Pediatr Nephrol 2005;20:499-506 https://doi.org/10.1007/s00467-004-1737-0
  10. O'Brien E. Demise of the mercury sphygmomanometer and the dawning of a new era in blood pressure measurement. Blood Press Monit 2003;8:19-21 https://doi.org/10.1097/00126097-200302000-00004
  11. Kaufmann MA, Pargger H, Drop LJ. Oscillometric blood pressure measurements by different devices are not interchangeable. Anesth Analg 1996;82:377-81 https://doi.org/10.1097/00000539-199602000-00029
  12. McNiece KL, Portman RJ. Ambulatory blood pressure monitoring: what a pediatrician should know. Curr Opin Pediatr 2007;19:178-82 https://doi.org/10.1097/MOP.0b013e328014671d
  13. Falkner B, Gidding SS, Ramirez-Garnica G, Wiltrout SA, West D, Rappaport EB. The relationship of body mass index and blood pressure in primary care pediatric patients. J Pediatr 2006;148:195-200 https://doi.org/10.1016/j.jpeds.2005.10.030
  14. Ribeiro J, Guerra S, Pinto A, Oliveira J, Duarte J, Mota J. Overweight and obesity in children and adolescents: relationship with blood pressure, and physical activity. Ann Hum Biol 2003;30:203-13 https://doi.org/10.1080/0301446021000054587
  15. Schiel R, Beltschikow W, Kramer G, Stein G. Overweight, obesity and elevated blood pressure in children and adolescents. Eur J Med Res 2006;11:97-101
  16. Chen AK, Roberts CK, Barnard RJ. Effect of a short-term diet and exercise intervention on metabolic syndrome in overweight children. Metabolism 2006;55:871-8 https://doi.org/10.1016/j.metabol.2006.03.001
  17. Monzavi R, Dreimane D, Geffner ME, Braun S, Conrad B, Klier M, et al. Improvement in risk factors for metabolic syndrome and insulin resistance in overweight youth who are treated with lifestyle intervention. Pediatrics 2006;117:e1111-8 https://doi.org/10.1542/peds.2005-1532
  18. ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group. Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). JAMA 2002;288:2981-97 https://doi.org/10.1001/jama.288.23.2981
  19. [No authors listed] After the diagnosis: adherence and persistence with hypertension therapy. Am J Manag Care 2005;11:S395-9
  20. Nilsson AB, Friberg P, Bonquist L, Lasaitiene D, Marcussen N, Chen Y. Growth hormone aggravates renal abnormalities induced by neonatal enalapril treatment. Pediatr Nephrol 2003;18:878-86 https://doi.org/10.1007/s00467-003-1197-y
  21. Nilsson AB, Nitescu N, Chen Y, Guron GS, Marcussen N, Matejka GL, et al. IGF-I treatment attenuates renal abnormalities induced by neonatal ACE inhibition. Am J Physiol Regul Integr Comp Physiol 2000;279:R1050-60 https://doi.org/10.1152/ajpregu.2000.279.3.R1050
  22. Gashti CN, Bakris GL. The role of calcium antagonists in chronic kidney disease. Curr Opin Nephrol Hypertens 2004;13:155-61 https://doi.org/10.1097/00041552-200403000-00003
  23. Bald M, Hoyer PF. Measurement of blood pressure at home: survey among pediatric nephrologists. Pediatr Nephrol 2001;16:1058-62 https://doi.org/10.1007/s004670100027
  24. Bald M, Bohm W, Feldhoff C, Bonzel KE. [Home blood pressure self-measurement in children and adolescents with renal replacement therapy]. Klin Padiatr 2001;213:21-5 https://doi.org/10.1055/s-2001-11268
  25. Gompels C, Savage D. Home blood pressure monitoring in diabetes. Arch Dis Child 1992;67:636-9 https://doi.org/10.1136/adc.67.5.636

Cited by

  1. Prescribing Patterns of Antihypertensives for Treatment-Naïve Patients in South Korea: From Korean NHISS Claim Data vol.2019, pp.None, 2019, https://doi.org/10.1155/2019/4735876