Analytical Science and Technology (분석과학)

The Korean Society of Analytical Sciences (한국분석과학회)
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The monitoring of some heavy metals in oriental mineral medicines

광물성 생약 중 중금속의 모니터링

  • Han, Eunjung (Center for Environmental Technology, Korea Institute of Science and Technology) ;
  • Chung, Jaeyeon (Center for Environmental Technology, Korea Institute of Science and Technology) ;
  • Park, Kyungsu (Advanced Analysis Center, Korea Institute of Science and Technology) ;
  • Kang, Inho (Herbal Medicine Evaluation Team, Korea Food and Drug Administration) ;
  • Kang, Sinjung (Herbal Medicine Evaluation Team, Korea Food and Drug Administration) ;
  • Kim, Yunje (Center for Environmental Technology, Korea Institute of Science and Technology)
  • 한은정 (한국과학기술연구원, 에너지환경연구본부, 환경기술연구단) ;
  • 정재연 (한국과학기술연구원, 에너지환경연구본부, 환경기술연구단) ;
  • 박경수 (한국과학기술연구원, 연구조정부, 특성분석센타) ;
  • 강인호 (식품의약안전청, 한약평가팀) ;
  • 강신정 (식품의약안전청, 한약평가팀) ;
  • 김연제 (한국과학기술연구원, 에너지환경연구본부, 환경기술연구단)
  • Received : 2008.07.18
  • Accepted : 2008.12.04
  • Published : 2008.12.25
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Abstract

This paper reports on the monitoring results of some heavy metals (Pb, Cd, As and Hg) in oriental mineral medicines. Levels of Pb, Cd and As were determined using the acid digestion method and ICP-MS. Hg levels were determined using the gold amalgamation method and Automatic mercury analyzer (AMA). The results indicated that, in the case of Pb, 25.81% (24 cases) of the samples were over MRL (5 mg/kg). Pb levels in Calamina, Pumex, and Cinnabaris exceeded MRL (5 mg/kg). In the case of Cd, 9.68% (17cases) of the samples were over MRL (0.3 mg/kg). Cd levels in Calamina, Pumex and Cinnabaris were exceeded MRL (0.3 mg/kg). In case of As, 24.73% (23 cases) of samples exceeded MRL (3 mg/kg). As levels in Calamina, Lithargyrum, Vermilionum, Cinnabaris and Chalcocitum exceeded MRL (3 mg/kg). In the case of Hg, it was shown that the 76.34% (78 cases) of the samples exceeded MRL (0.2 mg/kg). Hg levels in almost all the samples exceeded MRL (0.2 mg/kg). These results led us to recommend that the domestic commercial law to be legislated to ensure the quality estimation and safety of oriental mineral medicines.

본 연구에서는 시중에 유통중인 광물성 생약에서의 중금속(Pb, Cd, As, Hg)에 대해 모니터링 하였다. Pb, Cd, As의 경우 시료 전처리는 습식분해법으로 하였으며, ICP-MS를 이용하여 검출하였고 Hg의 경우 AMA를 이용하여 모니터링 하였다. 모니터링의 결과 전체 시료(92)의 25.81%(24)가 Pb를 함유하고 있었으며 능자광(85.5 mg/kg), 부석(41.2 mg/kg), 진사(20.4 mg/kg)에서 기준치(0.5 mg/kg) 이상으로 검출되었다. Cd의 경우 전체 시료(92)의 9.68%(17)가 함유되어있었으며, 능자광(345 mg/kg), 부석(0.44 mg/kg), 진사(2.78 mg/kg)에서 기준치(0.3 mg/kg) 이상으로 검출되었고, 전체 시료(92)의 24.73%(23)가 As를 함유하고 있었으며, 능자광(5.72 mg/kg), 조산화납(22.2 mg/kg), 황화제이수은(10.0 mg/kg), 진사(12.5 mg/kg), 흑운모(14.6 mg/kg)에서 기준치(3 mg/kg)이상으로 검출되었다. Hg의 경우는 전체 시료(92)의 76.34%(78)가 함유되어 있었으며, 전체 13 종 광물 중 10종에서 기준치(0.2 mg/kg) 이상으로 검출되었다. 따라서, 국내에 유통되고 있는 광물성 생약재의 품질 평가와 안전관리를 보완하여 광물성 생약에 대한 신뢰성과 안전성을 확보할 필요성이 있는 것으로 판단된다.

Keywords

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