대한의용생체공학회:의공학회지 (Journal of Biomedical Engineering Research)

  • 제29권6호
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  • Pages.415-430
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  • 2008
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  • 1229-0807(pISSN)
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  • 2288-9396(eISSN)
대한의용생체공학회 (The Korean Society of Medical and Biological Engineering)
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이식형 전자의료기 연구동향과 기술개발의 과제

Research Trends and Challenges in Technology Development of Medical Electronic Implant Devices

  • 조진호 (경북대학교 전자전기컴퓨터학부)
  • Cho, Jin-Ho (School of Electrical Engineering & Computer Science, Kyungpook National University)
  • 발행 : 2008.12.31
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초록

The technologies in medical electronic implant(MEI) devices are developing rapidly, and already, there are various kinds of the MEI devices in the current medical equipments market. Recently, the global market scale of MEI devices have been increased about 13% year by year, and the import amount of MEI devices in Korea is increasing rapidly. In the near future, the demands of MEI devices will be magnificently increasing by the continuous development of the biomedical electronics devices which coupled with neural, brain and other organs will bring us to tremendous effects, such as providing new therapeutic solutions to patients, extension and saving human life, and an important clue of medical development. However, the investment of the research and the activity of developments in this field are still very weak in the Korea. Consequently, this paper introduces about the research trends of MEI devices, and technological problems those must be solved, and then concludes with the suggestions in order to be the leading country in this field.

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참고문헌

  1. http://en.wikipedia.org/wiki/The_Age_of_Intelligent_Machines
  2. Electronic medical implants "Technical assessment and business strategies for the global market," Navigant consulting, Inc. 2004
  3. Sangmin Lee "Deep Brain Stimulation and Brain Machine Interface" Korea Science Foundation, Advanced Science technology Report, 2006
  4. R. Elmqvist et al. "Success Stories : Larsson, Arne" Arne, Avaiable at : http://www.sjm.com- /success- stories/successstory.aspx?name =Larsson,+Arne
  5. W. Graeatbatch et al. "History of implantable devices," IEEE Engineering in Medicine and Biology Magazine, vol. 10, no. 3, pp. 38-41, 1991
  6. W. Greatbatch et al. "Twenty-five Years of Pacemaking," Pacing and Clinical Electrophysiology, vol. 7, no. 1, pp. 143-147, 2006 https://doi.org/10.1111/j.1540-8159.1984.tb04872.x
  7. J. L Anderson et al. "Effect of prophylactic antiarrhythmic therapy on time to implantable cardioverter-defibrillator discharge in patients with ventricular tachyarrhythmias," The American Journal of Cardiology, vol 73, no. 9 pp. 683-687, 1994 https://doi.org/10.1016/0002-9149(94)90934-2
  8. R. D, Mitrani et al. "Cardiac pacemakers: Current and future status," Current Problems in Cardiology, vol. 24, no. 6, pp. 341- 420, 1999 https://doi.org/10.1016/S0146-2806(99)90002-6
  9. http://www.bostonscientific.com
  10. http://www.medtronic.com
  11. Heung-Chan Kim et al. "Ceramic size control for the improvement of small piezoelectric energy harvest," Korea Sensors Society, vol. 17, no. 4, pp. 267-272, 2008 https://doi.org/10.5369/JSST.2008.17.4.267
  12. A. P. Chandrakasan et al. "Ultralow-power electronics for biomedical applications," Annual Revision Biomedical Engineering, vol. 10, pp. 247-274, 2008 https://doi.org/10.1146/annurev.bioeng.10.061807.160547
  13. M. Lallart et al. "Double Synchronized Switch Harvesting (DSSH): A New Energy Harvesting Scheme for Efficient Energy Extraction," IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, vol. 55, no. 10, pp. 2119-2130, 2008 https://doi.org/10.1109/TUFFC.912
  14. M. Kahn, Heartbeats May power future Pacemakers, ABC News, 2008
  15. US. medical devices market outlook, frost & sullivan, 2008
  16. S. Xu et at. "A multi-channel telemetry system for brain micro stimulation in freely roaming animals," Journal of Neuroscience Methods, vol. 133, pp. 57-63, 2004 https://doi.org/10.1016/j.jneumeth.2003.09.012
  17. St. Jude Medical Receives FDA and CE Mark Approvals of Extended 10-Year Battery Life Claim for Rechargeable Neurostimulator
  18. R. Kumar et al. "Double-blind evaluation of subthalamic nucleus deep brain stimulation in advanced Parkinson's disease," Neurology, vol. 51, pp. 850-855, 1998 https://doi.org/10.1212/WNL.51.3.850
  19. J. L. Vi et al. "Mechanisms of deep brain stimulation: Excitation or inhibition," Movement Disorders, vol. 17, no. S3, pp. S69-S72, 2002 https://doi.org/10.1002/mds.10144
  20. http://www.wiredd.com
  21. A. Handforth et al. "Vagus nerve stimulation therapy for partialonset seizures," Neurology, vol. 51, pp. 48-55, 1998 https://doi.org/10.1212/WNL.51.1.48
  22. S. C. Schachter et al. "Vagus nerve stimulation," Epilepsia, vol. 39, no. 7, pp. 677-686, 2005
  23. E. Ganio et al. "Sacral nerve stimulation for treatment of fecal incontinence," Diseases of the Colon & Rectum, vol. 44, no. 5, pp. 619-629, 2005 https://doi.org/10.1007/BF02234555
  24. U. Jonas et al. "New Percutaneous Technique of Sacral Nerve Stimulation Has High Initial Success Rate: Preliminary Results," European Urology, vol. 43, no. 1, pp. 70, 2003 https://doi.org/10.1016/S0302-2838(02)00442-6
  25. J. C. Eagon et al. "Effect of electrical stimulation on gastric electrical activity, motility and emptying," Neurogastroenterol Motility, vol. 7, no, 1, pp. 39-45, 1995 https://doi.org/10.1111/j.1365-2982.1995.tb00207.x
  26. J. Dargent et al. "Gastric Electrical Stimulation as Therapy of Morbid Obesity: Preliminary Results from the French Study," Obesity Surgery, vol. 12, no. 1, pp. 21-25, 2002 https://doi.org/10.1381/096089202762552638
  27. http://www.cochlear.com
  28. D. D. Greenwood et al. "A cochlear frequency-position function for several species 29 years later," The Journal of the Acoustical Society of America, vol. 87, no. 6, pp. 2592-2605, 1990 https://doi.org/10.1121/1.399052
  29. B. wilson et al. "Better speech recognition with cochlear implants," Nature, vol. 252, pp. 236-238, 1991
  30. C. Toumazou, et al. "Micropower log-domain filter for electronic cochlea," Electronics, vol. 30, no. 22, pp. 1839-1841, 2002
  31. J. H. Spindel et al. "Round window electromagnetic implantable hearing aid," United States Patent 5360388
  32. J. Kiefer et al. "Round Window Stimulation with an Implantable Hearing Aid (Soundbridge$\bigcircR$) Combined with Autogenous Reconstruction of the Auricle - A New Approach," Journal for Oto- Rhino-Laryngology and its realted specialties, vol. 68, no. 6, 2006
  33. http://www.otologics.com
  34. http://www.scrmc.org/
  35. http://www.hhmi.org/senses/b150.html
  36. V. D. Chase, "Seeing is Believing", Technology Review, pp. 44-55, 1999
  37. http://www.hbs.edu/units/tom/conferences/docs/Visual%20 Prosthetic%20Device.pdf
  38. E. Zrenner, "Will Retinal Implants Restore Vision?" Science, vol. 295, pp. 1022-1025, 2002 https://doi.org/10.1126/science.1067996
  39. R. A. Normann et al. "Cortical Implants for the blind", IEEE Spectrum, pp. 54-59, May 1996
  40. http://www.usc.edu/
  41. http://www.utah.edu
  42. http://www.meei.harvard.edu
  43. M. A. Lebedev et al. "Brain machine interfaces: past, present and future, Neurosciences, vol. 29, no. 9, pp. 536-546, 2006 https://doi.org/10.1016/j.tins.2006.07.004
  44. S. K. An, et al. "Design for a Simplified Cochlear Implant System," IEEE transactions on biomedical engineering, vol. 54, NO. 6, pp. 973-JUNE 2007 https://doi.org/10.1109/TBME.2007.895372
  45. http://www.doheny.org
  46. P. J. Rousche et al. "Chronic Intracortical Microstimulation (ICMS) of Cat Sensory Cortex Using the Utah Intracortical Electrode Array," IEEE Transaction on rehabilitation engineering, vol. 7, NO. 1, MARCH, pp.56-68, 1999 https://doi.org/10.1109/86.750552
  47. http://nanobio.snu.ac.kr
  48. L. Highleyman et al. "Disease Progression: What is Fibrosis?," HCSP, 2007
  49. V. Lovat et al. "Carbon Nanotube Substrate Boost Neural Electrical Signaling," Nano Letters, vol.5, no, 6, pp. 1107-1110, 2007 https://doi.org/10.1021/nl050637m
  50. Sang-Cheu Naml, " Lithium Battery for Body implant Medical Devices," Journal of power sources, vol. 162, pp. 837, 2006 https://doi.org/10.1016/j.jpowsour.2005.07.018
  51. E. Takeuchi et al. "Lithium Batteries for Biomedical Application," MRS bulletin, vol. 27, no. 8, pp. 624-627, 2002 https://doi.org/10.1557/mrs2002.199
  52. C. Holmes et al. "The Role of lithium batteries in modern health care," Journal of Power sources, vol. 97, pp. 97-98, 2001 https://doi.org/10.1016/S0378-7753(01)00596-1
  53. G. Nazri et al. "Lithium Batteries Science and Technology," Kluwer Academic Publishers, 2004
  54. P. Si, et al. "A frequency control method for regulating wireless power to implantable devices," IEEE Transactionson biomedical circuits and systems, vol. 2, no. 1, pp. 22-29, 2008 https://doi.org/10.1109/TBCAS.2008.918284
  55. International Commission on Non-Ionizing Radiation Protection (ICNIR), Health Phys, vol. 74, no. 4, pp. 494-522, 1998
  56. C. K. Liang, et al. "An implantable bi-directional wireless transmission system for transcutaneous biological signal recording," Physiological Measurement, vol. 26, pp. 83-97, 2005 https://doi.org/10.1088/0967-3334/26/1/008
  57. T. Ozeki et al. "A Study on an Energy Supply Method for a Transcutaneous Energy Transmission System," Artificial organs, vol. 27, no. 1, pp. 68-72, 2003 https://doi.org/10.1046/j.1525-1594.2003.07179.x
  58. C. M. Zierhofer et al. "High-Efficiency Coupling-Insensitive Transcutaneous Power and Data Transmission Via an Inductive Link," IEEE transaction on biomedical engineering, vol. 37, no. 7, pp. 716-722, 1990 https://doi.org/10.1109/10.55682
  59. B. Lenaerts et al. "An inductive power link for a wireless endoscope," biosensors and bioelectronics, vol. 22, pp. 1390-1395, 2007 https://doi.org/10.1016/j.bios.2006.06.015
  60. http://www.pacaero.com/
  61. Federal Communications Commission (FCC), 47 CFR 95.601- 95.673 subpart E Rules applicable to MICS
  62. Jong-Ok Joo, " Frequency allocation of the living life purpose wireless equipment for the U-life era," Report Materials of Korea Ministry of Information and Communication, pp. 1-6, 2007
  63. http://www.ieee802.org/15/
  64. IEEE standard for safety levels with respect to human exposure to radio frequency electromagnetic field, 3 KHz to 300 GHz, IEEE Std. C95.1, 1999
  65. Jong-Soo Cho, "Functional Biomaterial Science", Freedom Academy, Seoul, 2007
  66. K. C. Cheung et al. "Comparison of tissue reaction to implanted polyimide and silicon microelectrode arrays." BiosurfaceVI - Tissue-Surface Interaction, Switzerland, 2005
  67. S. R. Montezuma et al. "Biocompatibility of materials Implants into the Subretinal Space of Yucatan Pigs", Invertigative Ophthalmology and Visual Science, vol. 47, no. 8, pp. 3514-3522 2004
  68. Y. Zhong et al. "A novel dexamethasone-releasing, anti-inflammatorycoating for neural im- plants," 2nd International IEEE EMBS Conference on Neural Engineering, pp. 120-125, 2005
  69. http://www.hbs.edu/units/tom/conferences/docs/Visual%20 Prosthetic%20Device.pdf
  70. S. H. Lee et al. " Stable deposition and patterning of metal layers on the PDMS substrate and characterization for the development of the flexible and implantable micro electrode" Solid state phenomena, vol. 124-126, pp.165-168, 2007 https://doi.org/10.4028/www.scientific.net/SSP.124-126.165