Journal of the Korean Association of Oral and Maxillofacial Surgeons

The Korean Association of Oral and Maxillofacial Surgeons (대한구강악안면외과학회)
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OSTEOBLASTOMA OF THE MANDIBLE : A CASE REPORT

하악골에 발생한 골아세포종의 치험례

  • Jeong, Se-Heon (Department of Oral & Maxillofacial Surgery, St. Mary's Hospital, The Catholic University of Korea) ;
  • Yoon, Hyun-Joong (Department of Oral & Maxillofacial Surgery, St. Mary's Hospital, The Catholic University of Korea) ;
  • Lee, Sang-Hwa (Department of Oral & Maxillofacial Surgery, St. Mary's Hospital, The Catholic University of Korea)
  • 정세헌 (가톨릭대학교 성모병원 구강악안면외과) ;
  • 윤현중 (가톨릭대학교 성모병원 구강악안면외과) ;
  • 이상화 (가톨릭대학교 성모병원 구강악안면외과)
  • Published : 2008.12.31
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Abstract

Osteoblastoma is a relatively rare benign bone tumor representing less than 1% of all bone tumors. The tumor usually involves the spine and sacrum of young individuals, less than 10% being localized to the skull, and nearly half of these affect the mandible, especially the posterior segments. In clinical finding, osteoblastoma present mainly with pain, swelling, and expansion of bone cortex. Radiographic appearances are variable, but frequently a well-delineated radiolucent lesion containing varying amounts of mineral deposits is seen. Histologically, ostoeblastoma is consists of irregular trabeculeae of osteoid and immature bone present within highly vascular connective tissue matrix. Osteoblastoma must be differentiated from a number of bone-producing lesions, including osteoid osteoma, fibrous dysplasia, ossifying fibroma, fibrous dysplasia, and osteosarcoma. If diagnosis may be mistaken for osteosarcoma, there are risks of more aggressive and irreversible treatment. Differential diagnosis of osteoblastoma is important. The preferred treatment of osteoblastoma is conservative approach and surgical excision. Recurrence following surgical intervention is rare. We treated osteoblastoma located in premolar area of mandible by excision with preservation of vital structure, such as nerves and teeth. So we report our clinical treatment with literature review

Keywords

References

  1. Lichtestein L, Sawyer WR. Benign osteoblastoma: further observations and report of twenty additional cases. J Bone Joint Surg Am 1964; 46: 755-765 https://doi.org/10.2106/00004623-196446040-00005
  2. Regezi JA, Sciubba JJ. Oral pathology: clinical-pathologic correlations. 2nd ed. Philadelphia: WB Saunders; 1993. 404-406
  3. Ahmed MS, Nwoku AL. Benign osteoblastoma of the mandibular ramus: review of the literature and report of a case. J Oral Maxillofac Surg 2000; 58: 1310-1317 https://doi.org/10.1053/joms.2000.16637
  4. Gordon SC, MacIntosh RB. Wesley RKO. A review of osteoblastoma and case report of metachronous osteoblastoma and unicystic ameloblastoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2001; 91: 570-575 https://doi.org/10.1067/moe.2001.113349
  5. Haug RH, Huaer C, De Camillo AJ, Araneta M. Benign osteoblastoma of the mandible: report of a case. J Oral Maxillofac Surg 1990; 48: 743-748 https://doi.org/10.1016/0278-2391(90)90064-9
  6. Mirra JM, Picci P, Gold RH. Bone tumors. Clinical, radiologic and pathologic correlations. Philadelphia: Lea & Febiger; 1989. 389-430
  7. Berotoni FD, Unni KK, Lucas DR, Osteosarcoma resembling osteoblastoma. Cancer 55:416-426,1985 https://doi.org/10.1002/1097-0142(19850115)55:2<416::AID-CNCR2820550221>3.0.CO;2-5
  8. Berotoni F, Bacchhini P, Donati D, Maetini A, Picci P, Campanacci M. Osteoblastoma-like osteosarcoma. Modern Pathol 6:707-716, 1993
  9. I Van der Waal, RB Greebe and EA Elias. Benign osteoblastoma or osteoid osteoma of the maxilla: report of a case. Int J Oral Surg 12 (1983), 355-358 https://doi.org/10.1016/S0300-9785(83)80026-X
  10. Lichtenstein L. Benign osteoblastoma: a category of osteoid and bone-forming tumors other than classical osteoid osteoma, which may be mistaken for giant-cell tumor or osteogenic sarcoma. Cancer 1956; 9: 1044-1052 https://doi.org/10.1002/1097-0142(195609/10)9:5<1044::AID-CNCR2820090523>3.0.CO;2-O
  11. El-Mofty S, Refai H. Benign osteoblastoma of the maxilla. J Oral Maxillofac Surg 1989; 47: 60-64
  12. Strand-Pettinen I, Lukinmaa PL, Holmtrom T, Lindqvist C, Hietanen J. Benign osteoblastoma of the mandible. Br J Oral Maxillofac Surg 1990; 28: 311-316 https://doi.org/10.1016/0266-4356(90)90105-T
  13. Asada Y, Suzuki I, Suzuki M, Fukushima M. Atypical multiple benign osteoblastomas accompanied by simple bone cysts. J Craniomaxillofac Surg 1991; 19: 166-171 https://doi.org/10.1016/S1010-5182(05)80307-5
  14. Capodiferro S, Maiorano E, Giardina C, Lacaita MG, Lo Muzio L, Favia G. Osteoblastoma of the mandible: clinicopathologic study of four cases and literature review. Head Neck. 2005 Jul;27(7):616-21. Review https://doi.org/10.1002/hed.20192
  15. R.A. Smith, L.S. Hansen, D. Resnick and W. Chan. Comparison of the osteoblastoma in gnathic and extragnathic sites, Oral Surgery, Oral Medicine, Oral Pathology 54 (1982), 285 https://doi.org/10.1016/0030-4220(82)90098-6
  16. S. Weinberg, N. Katsikeris and M. Pharoah. Osteoblastoma of the mandibular condyle: Review of the literature and report of a case, Journal of Oral and Maxillofacial Surgery 45 (1987), 350 https://doi.org/10.1016/0278-2391(87)90359-4
  17. Regezi JA, Sciubba JJ. Oral pathology: clinical-pathologic correlations. 2nd ed. Philadelphia: WB Saunders; 1989:322,375
  18. Nevill et al , Saunders : Oral and maxillofacial pathology 2nd edition 2002, 568-570
  19. A.G. Huvos. Bone Tumors. Diagnosis, Treatment and Prognosis, Saunders, Philadelphia & London (1979), 33-46
  20. Ribera MJ. Osteoblastoma in the anterior maxilla mimicking periapical pathosis of odontogenic origin. J Endodont 1996; 22: 142-146 https://doi.org/10.1016/S0099-2399(96)80292-5
  21. 이성근, 정인교, 박혜련. 하악골에서 발생한 골아세포종을 닮은 골육종의 치험1례. 대한악안면성형재건외과학회지: Vol.22, No.3, 2000
  22. Borrelo ED, Sedano HO. Giant osteoid osteoma of the maxilla. Oral Surgery, Oral Medicine, Oral Pathology 23 (1967), 563-566 https://doi.org/10.1016/0030-4220(67)90334-9
  23. Remagen W, Prein J: Benign osteoblastoma. Oral Surgery, Oral Medicine, Oral Pathology 39 (1975), 279-283 https://doi.org/10.1016/0030-4220(75)90229-7
  24. HS Kramer. Benign osteoblastoma of the mandible: report of a case. Oral Surg Oral Med Oral Pathol 24 (1967), 842-851 https://doi.org/10.1016/0030-4220(67)90524-5
  25. Alvares Capelozza, Giao Dezotti. Osteoblastoma of mandible: systemic review of the literature and report of a case. Dentomaxillofacial Radiology (2005)34, 1-8 https://doi.org/10.1259/dmfr/24385194