Clinical Characteristics and Outcome Predictor of Hypertensive Intracerebral Hemorrhage in the Very Elderly

초고령 노인들에서 고혈압성 뇌출혈의 임상적 특징 및 예후 인자

Objective : We investigated clinical characteristics and independent outcome predictors of hypertensive intracerebral hemorrhage(ICH) in the very elderly patients. Methods : From January 2001 to December 2005, we analyzed retrospectively 28 very elderly patients(${\geq}$ 80 years) with hypertensive ICH admitted to our neurosurgical department. As a control group, 200 younger patients(<80 years) with hypertensive ICH were selected. We analyzed risk factors, clinical and radiologic characteristics, outcomes of hypertensive ICH in very elderly. Multivariate logistic regression analyses were performed to find out independent predictors of 30-day mortality. Results : Diastolic blood pressure, white blood cell counts and serum albumin on admission were significantly lower among patients ${\geq}$ 80 years than in the control group(all p<0.05). Thirty-day mortality was higher among patients ${\geq}$ 80 years than in the control group(35.7% vs. 19.0%, respectively, p = 0.005). By multivariate analysis, in ICH patients ${\geq}$ 80 years, only coma(Glasgow coma scale score ${\leq}$ 8) was independently associated with 30-day mortality(odds ratio[OR]25.5, 95% confidence interval[CI]2.36 - 275.74, p<0.001). Conclusion : Our result suggests that the very elderly patients with hypertensive ICH may present some different clinical characteristics from those in their younger counterparts.