Clinical Application of $^{18}F-FDG$ PET in Breast Cancer

유방암에서 $^{18}F-FDG$ PET의 임상 이용

  • Yoon, Joon-Kee (Department of Nuclear Medicine and Molecular Imaging, Ajou University School of Medicine)
  • 윤준기 (아주대학교 의과대학 핵의학교실)
  • Published : 2008.12.31

Abstract

$^{18}F-FDG$ PET in combination with conventional imaging modalities could help avoid unnecessary biopsy for the primary mass, and it also has a high diagnostic accuracy in patients with dense breasts. In the assessment of metastasis, $^{18}F-FDG$ PET was useful to select patients who required sentinel lymph node biopsy and to detect extra-axillary lymph node metastasis and distant metastasis. To increase the sensitivity for osteoblastic bone metastasis, bone scintigraphy should be added. In the detection of recurrence, $^{18}F-FDG$ PET showed a higher diagnostic accuracy than tumor marker or computed tomography, and therefore it can be used in routine breast cancer follow-up. $^{18}F-FDG$ PET has been reported that it correctly predicted the response of neoadjuvant chemotherapy on as early as 8th day of treatment. Therefore, it is useful for the early detect of therapeutic response in advanced breast cancer.

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