Design and Evaluation of Cardiovascular Impedance Simulator Considering Mechanical Limits

기계적 한계를 고려한 심혈관 순환계 임피던스 시뮬레이터 설계 및 평가

  • 곽관웅 (세종대학교 기계공학과)
  • Published : 2008.01.01

Abstract

The parameter-based cardiovascular impedance simulator that is able to overcome the limits of conventional mock circulatory systems is critical for the development and test of biomedical devices including artificial heart. The concept of impedance simulator was validated mathematically in a previous study using high-gain feedback linearization control which, however, may cause serious difficulties and limits for practical implementation. In this study, therefore, practical applicability of the impedance simulator is investigated considering the physical limits such as motor speed and torque. Simple PID controller which do not require complex model of the simulator is used considering the practical implementation. Design guidelines of the impedance simulator are also provided based on the results.

Keywords

References

  1. Ferrari, G., De Lazzri, C., Mimmo, R., Tosti, G., Ambrosi, D. and Gorczynska, K., 'A Computer Controlled Mock Circulatory Sysem for Mono and Biventricular Assist Device Testing,' International Journal of Artificial Organs, Vol. 21, No. 1, pp. 26-36, 1998 https://doi.org/10.1177/039139889802106s06
  2. Lehman, K. A., Antaki, J. F., Woodard, J. C. and Boston, J. R., 'A Starling-Responsive Mock Circulatory Loop for the Ventricular Assist Hamodynamic Simulation,' Waseda International Congress of Modeling and Simulation Technology for Artificial Organs, pp. 105-106, 1996
  3. Rosenberg, G., Phillips, W. M., Landis, D. L. and Pierce, W. S., 'Design and Evaluation of the Pennsylvania State University Mock Circulatory System,' ASAIO Journal, Vol. 4, No. 1, pp. 41-49, 1981
  4. Williams, J. L., Antaki, J. F., Boston, J. R., Williams, S. L., Woodward, J. C., Miller, P. J. and Kornos, R. L., 'Load Sensitive Mock Circulatory System for Left Ventricular Assist Device Controller Evaluation and Development,' Proceedings of the 16th Annual International Conference for the IEEE Engineering in Medicine and Biology Society, pp. 89-90, 1994
  5. Loh, M. and Yu, Y., 'Feedback Control Design of an Elastance-Based Mock Circulatory System for Heart Assist Device Controller Development,' under review, American Control Conference, pp. 1639-1644, 2004
  6. Baloa, L. A., Boston, J. R. and Antaki, J. F., 'Elastance-Based Control of a Mock Circulatory System,' Annals of Biomedical Engineering, Vol. 29, No. 3, pp. 244-251, 2001 https://doi.org/10.1114/1.1355275
  7. Liu, Y., Allure, P., Wood, H. and Olson, D., 'Construction of an Artificial Heart Pump Performance Test System,' Cardiovascular Eng., Vol. 6, No. 4, pp. 153-160, 2006
  8. Gwak, K. W., Paden, B., Noh, M. and Antaki, J., 'Fluidic Operational Amplifier for Mock Circulatory Systems,' IEEE Trans Control Systems Technology, Vol. 14, No. 4, pp. 602-612, 2006 https://doi.org/10.1109/TCST.2006.876624
  9. Choi, S., 'Modeling and Control of left Ventricular Assist System,' Ph.D. Thesis, University of Pittsburgh, 1998
  10. Suga, H. and Sagawa, K., 'Instantaneous Pressure-Volume Relationships and their ratio in the excised, supported canine left ventricle,' Circulation Research, Vol. 35, No. 1, pp. 117-126, 1974 https://doi.org/10.1161/01.RES.35.1.117
  11. Sagawa, K., Maugahan, L., Suga, H. and Sunagawa, K., 'Cardiac Contraction and the Pressure-Volume Relationship,' Cardiac Contraction and the Pressure-Volume Relationship, Oxford University Press, pp. 42-109, 1988
  12. Guyton, A. C. and Hall, J. E., 'Textbook of Medical Physiology,' 10th ed, Saunders, pp. 96-264, 2000