Journal of Preventive Medicine and Public Health

  • 제41권6호
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  • Pages.397-406
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  • 2008
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  • 1975-8375(pISSN)
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  • 2233-4521(eISSN)
대한예방의학회 (The Korean Society for Preventive Medicine)
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신경독성물질에 의한 신경계장애 조기발견을 위한 색각검사의 활용가능성

Usefulness of Color Vision Test for Early Detection of Neurological Damages by Neurotoxic Substances

  • 이은희 (서울대학교 보건환경연구소) ;
  • 최경호 (서울대학교 보건환경연구소) ;
  • 채홍재 (전남대학병원 산업의학과) ;
  • 백도명 (서울대학교 보건환경연구소)
  • Lee, Eun-Hee (Institute of Health and Environment, Seoul National University) ;
  • Choi, Kyung-Ho (Institute of Health and Environment, Seoul National University) ;
  • Chae, Hong-Jae (Occupational & Environmental Medicine, Chonnam National University) ;
  • Paek, Do-Myung (Institute of Health and Environment, Seoul National University)
  • 발행 : 2008.11.30
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초록

This paper reviews the published literature that is concerned with color vision impairment from industrial and environmental exposure to neurotoxic substances, and we evaluated whether testing for color vision impairment could be an affordable procedure for assessing these neurotoxic effects. In general, most cases of congenital color vision impairment are red-green, and blue-yellow impairment is extremely rare. However, most of the acquired color vision impairment that is related to age, alcohol or environmental factors is blue-yellow impairment. Therefore, many studies have been performed to identify this relationship between exposure to neurotoxic substances, such as organic solvents and heavy metals, and the prevalence of blue-yellow color vision impairment. The test for color vision impairment is known to be very sensitive to the early signs of nervous system dysfunction and this can be useful for making the early diagnosis of neurotoxic effects from exposure to very low concentrations of toxic substances.

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