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Skull Base Invasion of Adenoid Cystic Carcinoma of the Lacrimal Gland : A Case Report

  • Lee, Jae-Il (Department of Neurosurgery, Masan Samsung Hospital, Sungkyunkwan University School of Medicine) ;
  • Kim, Young-Zoon (Department of Neurosurgery, Masan Samsung Hospital, Sungkyunkwan University School of Medicine) ;
  • Lee, Eun-Hee (Department of Pathology, Masan Samsung Hospital, Sungkyunkwan University School of Medicine) ;
  • Kim, Kyu-Hong (Department of Neurosurgery, Masan Samsung Hospital, Sungkyunkwan University School of Medicine)
  • 발행 : 2008.10.28

초록

Although adenoid cystic carcinoma (ACC) of the lacrimal gland is a rarely encountered orbital tumor, it invades intracranially more frequently than carcinomas of other glands in the head and neck. A 52-year-old man underwent orbital exenteration and resection of intracranially extended tumor via a fronto-orbito-zygomatic approach in combination with a transfacial approach. Histopathologically, the tumor showed perineural, vascular, and lymphatic invasion. Additionally, he received radiotherapy (60 Gy) and adjuvant systemic cisplatin and 5-fluorouracil chemotherapy due to residual tumor in the orbit and systemic metastases (lung, ribs, and spines). He was free of progression and recurrence at 6 months after treatment. The authors report a case of skull base invasion by an ACC of the lacrimal gland to remind neurosurgeons planning intervention that this disease shows a tendency to invade intracranially.

키워드

참고문헌

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피인용 문헌

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  3. Expression of survivin in adenoid cystic carcinoma of the lacrimal gland and the effect of intervention with arsenic trioxide in vitro vol.10, pp.1, 2008, https://doi.org/10.3892/etm.2015.2466