Herbal Formula Science (대한한의학방제학회지)

The Korean Medicine Society for the Herbal Formula Study (대한한의학방제학회)
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Mouse Models of Atopic Dermatitis for Drug Discovery from Medicinal Plants

아토피 피부염 치료제 개발에 활용할 수 있는 마우스 모델에 대한 고찰

  • Yun, Young-Gab (Department of Oriental Medical Prescription, Wonkwang University) ;
  • Hwang, Joo-Min (Department of Oriental Medical Prescription, Wonkwang University) ;
  • Kim, Hyung-Rul (Department of Oriental Medical Prescription, Wonkwang University) ;
  • Jang, Seon-Il (School of Alternative Medicine & Health Science, College of Alternative Medicine, Jeonju University)
  • 윤용갑 (원광대학교 한의과대학 방제학교실) ;
  • 황주민 (원광대학교 한의과대학 방제학교실) ;
  • 김형률 (원광대학교 한의과대학 방제학교실) ;
  • 장선일 (전주대학교 대체의학대학 대체건강관리학부)
  • Published : 2007.06.30
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Abstract

Atopic dermatitis (AD) is a chronic inflammatory skin disease associated with cutaneous hyperreactivity to environmental triggers. The clinical phenotype that characterizes AD is the product of interactions between susceptible genes, the environmental factors, defective skin barrier function, and immunologic responses. This review summarizes recent progress in our understanding of the immunopathophysiology of AD and the implications for mouse models of AD in drug discovery from medicinal plants.

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