The Journal of Internal Korean Medicine (대한한방내과학회지)

The Society of Internal Korean Medicine (대한한방내과학회)
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Experimental Studies on the Anti-cathartic Effects of Bojangjisa-tang

보장지사탕의 항사하작용에 관한 연구

  • Lee, Seon-Young (Dept. of Internal Medicine, College of Oriental Medicine, Kyung-Hee University) ;
  • Park, Jae-Woo (Dept. of Internal Medicine, College of Oriental Medicine, Kyung-Hee University) ;
  • Ryu, Bong-Ha (Dept. of Internal Medicine, College of Oriental Medicine, Kyung-Hee University)
  • 이선령 (경희대학교 한의과대학 비계내과학 교실) ;
  • 박재우 (경희대학교 한의과대학 비계내과학 교실) ;
  • 류봉하 (경희대학교 한의과대학 비계내과학 교실)
  • Published : 2007.06.30
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Abstract

Objectives : The aim of this experimental study was to investigate the effects of Bojangjisa-tang on anticatharsis by using mice and Guinea pigs. Methods : We observed the actions on gastrointestinal smooth muscles, on the transportability of small and large intestines and on diarrhea induced by castor oil, philocarpine, and barium chloride. Results : Bojangjisa-tang showed alleviation of the contraction of gastrointestinal smooth muscles induced by acetylcholine chloride and barium chloride. The transportability of the large intestine was constrained by Bojangjisa-tang, which also showed substantial anti-cathartic effects on diarrhea induced by castor oil, philocarpine and barium chloride. Conclusion : These results demostrate that Bojangjisa-tang has advantageous effects on drug-induced diarrhea and will contribute to the development of diarrhea treatment through further related studies.

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