대한한방내과학회지 (The Journal of Internal Korean Medicine)
- 제28권1호
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- Pages.166-175
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- 2007
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- 1226-9174(pISSN)
대계와 실리비닌의 Mouse BV2 Microglial Cells에서 Lipopolysaccharide에 의해 유발된 염증반응에 대한 신경보호 효과
Neuroprotective Effect of Cirsium japonicum and Silibinin on Lipopolysaccharide-induced Inflammation in BV2 Microglial Cells
- 여현수 (경원대학교 한의과대학 내과학교실) ;
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김동우
(경원대학교 한의과대학 내과학교실) ;
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전찬용
(경원대학교 한의과대학 내과학교실) ;
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최유경
(경원대학교 한의과대학 내과학교실) ;
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박종형
(경원대학교 한의과대학 내과학교실)
- Yeo, Hyun-Soo (Department of Internal Medicine, College of Oriental Medicine, Kyungwon University) ;
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Kim, Dong-Woo
(Department of Internal Medicine, College of Oriental Medicine, Kyungwon University) ;
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Jun, Chan-Yong
(Department of Internal Medicine, College of Oriental Medicine, Kyungwon University) ;
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Choi, You-Kyung
(Department of Internal Medicine, College of Oriental Medicine, Kyungwon University) ;
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Park, Chong-Hyeong
(Department of Internal Medicine, College of Oriental Medicine, Kyungwon University)
- 발행 : 2007.03.31
초록
Objectives : This study was designed to evaluate the neuroprotective effect of Cirsium japonicum and Silibinin on lipopolysaccharide-induced inflammation in BV2 microglial cells. Methods : We studied on the neuroprotective effect of lipopolysaccharide-induced inflammation using MTS assay, western blot, and nitric oxide detection on mouse BV2 microglial cells. Results : Cirsium japonicum dose-dependently (50