The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology (한방안이비인후피부과학회지)
- Volume 20 Issue 1 Serial No. 32
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- Pages.169-176
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- 2007
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- 1738-6640(pISSN)
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- 2234-4020(eISSN)
Study of Gagamtongsung-San about cytotoxicity in L1210
가감통선산(加減通聖散)의 여러 가지 분획에 따른 L1210 암(癌) 세포주(細胞株) 억제(抑制) 효과(效果)
Abstract
Objectives : The purpose of this study was to investigate inhibitory effect of Gagamtongsung-San(GTS) on the cancer. Methods : This study estimated the cytotoxicity of GTS about L1210 and NIH3T3. We used GTS extract distilled with water, n-Hexane, Ethyl acetate and Butanol. The cytotoxicitys of GTS about cancer cells and normal cells were tested using a colorimetric tetrazoliun assay(MTT assay). Results : The results of this study were obtained as follow ; l. Cytotoxicity of water extract of GTS in L1210 cell lines was significantly increased, compared with NIH3T3. 2. n-Hexane fraction of GTS had similar cytotoxicity between L1210 and NIH3T3, and that have similar